Candidate gene analysis of the surfactant protein D gene in pediatric diffuse lung disease.
J Pediatr
; 163(6): 1778-80, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-23932215
ABSTRACT
Mutations in surfactant-associated genes cause childhood diffuse lung disease. Mice lacking surfactant protein D develop lung disease with age. However, we identified no novel surfactant protein D gene (SFTPD) coding or splice region variants in 73 unrelated children with diffuse lung disease from a cohort enriched for genetic surfactant dysfunction.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteína D Associada a Surfactante Pulmonar
/
Estudos de Associação Genética
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Pneumopatias
Tipo de estudo:
Observational_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Child
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Child, preschool
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Humans
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Infant
Idioma:
En
Revista:
J Pediatr
Ano de publicação:
2013
Tipo de documento:
Article