High-dose atorvastatin reduces periodontal inflammation: a novel pleiotropic effect of statins.

Subramanian, Sharath; Emami, Hamed; Vucic, Esad; Singh, Parmanand; Vijayakumar, Jayanthi; Fifer, Kenneth M; Alon, Achilles; Shankar, Sudha S; Farkouh, Michael; Rudd, James H F; Fayad, Zahi A; Van Dyke, Thomas E; Tawakol, Ahmed

Subramanian, Sharath; Emami, Hamed; Vucic, Esad; Singh, Parmanand; Vijayakumar, Jayanthi; Fifer, Kenneth M; Alon, Achilles; Shankar, Sudha S; Farkouh, Michael; Rudd, James H F; Fayad, Zahi A; Van Dyke, Thomas E; Tawakol, Ahmed.

Afiliação

Subramanian S; Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Emami H; Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Vucic E; Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Singh P; Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Vijayakumar J; Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Fifer KM; Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Alon A; Merck Sharp & Dohme Corp., Whitehouse Station, New Jersey.
Shankar SS; Merck Sharp & Dohme Corp., Whitehouse Station, New Jersey.
Farkouh M; Peter Munk Cardiac Centre and the Heart and Stroke Richard Lewar Centre of Excellence, the University of Toronto, Toronto, Ontario, Canada.
Rudd JHF; Division of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom.
Fayad ZA; Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
Van Dyke TE; Forsyth Institute, Cambridge, Massachusetts.
Tawakol A; Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address: atawakol@partners.org.

J Am Coll Cardiol ; 62(25): 2382-2391, 2013 Dec 24.

Article em En | MEDLINE | ID: mdl-24070911

Assuntos

Ácidos Heptanoicos/administração & dosagem; Inibidores de Hidroximetilglutaril-CoA Redutases/administração & dosagem; Doenças Periodontais/diagnóstico; Doenças Periodontais/tratamento farmacológico; Pirróis/administração & dosagem; Adulto; Idoso; Idoso de 80 Anos ou mais; Atorvastatina; Método Duplo-Cego; Feminino; Humanos; Inflamação/diagnóstico; Inflamação/tratamento farmacológico; Masculino; Pessoa de Meia-Idade; Resultado do Tratamento

Palavras-chave

(18)F-fluorodeoxyglucose; C-reactive protein; CRP; CT; FDG; HDL; LDL-C; PD; PET; ROI; SUV; TBR; atherosclerosis; computed tomography; high-density lipoprotein; imaging; inflammation; low-density lipoprotein cholesterol; nuclear medicine; periodontal disease; positron emission tomography; region of interest; standardized uptake value; statins; target-to-background ratio

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Periodontais / Pirróis / Inibidores de Hidroximetilglutaril-CoA Redutases / Ácidos Heptanoicos Tipo de estudo: Clinical_trials / Diagnostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Am Coll Cardiol Ano de publicação: 2013 Tipo de documento: Article

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