TbGT8 is a bifunctional glycosyltransferase that elaborates N-linked glycans on a protein phosphatase AcP115 and a GPI-anchor modifying glycan in Trypanosoma brucei.

Nakanishi, Masayuki; Karasudani, Moe; Shiraishi, Takahiro; Hashida, Kazunori; Hino, Mami; Ferguson, Michael A J; Nomoto, Hiroshi

Nakanishi, Masayuki; Karasudani, Moe; Shiraishi, Takahiro; Hashida, Kazunori; Hino, Mami; Ferguson, Michael A J; Nomoto, Hiroshi.

Afiliação

Nakanishi M; Laboratory of Biochemistry, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime 790-8578, Japan. Electronic address: mnakanis@cc.matsuyama-u.ac.jp.
Karasudani M; Laboratory of Biochemistry, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime 790-8578, Japan.
Shiraishi T; Laboratory of Biochemistry, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime 790-8578, Japan.
Hashida K; Laboratory of Biochemistry, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime 790-8578, Japan.
Hino M; Laboratory of Biochemistry, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime 790-8578, Japan.
Ferguson MA; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.
Nomoto H; Laboratory of Biochemistry, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime 790-8578, Japan.

Parasitol Int ; 63(3): 513-8, 2014 Jun.

Article em En | MEDLINE | ID: mdl-24508870

Assuntos

Glicosiltransferases/metabolismo; Fosfoproteínas Fosfatases/metabolismo; Polissacarídeos/metabolismo; Proteínas de Protozoários/metabolismo; Trypanosoma brucei brucei/enzimologia; Western Blotting; Glicosilação; Glicosiltransferases/genética; Fosfoproteínas Fosfatases/genética; Lectinas de Plantas/metabolismo; Reação em Cadeia da Polimerase; Polissacarídeos/genética; Proteômica; Proteínas de Protozoários/genética; Trypanosoma brucei brucei/genética

Palavras-chave

GPI-anchor; Glycosyltransferase; N-linked glycan; Tomato lectin; Trypanosoma brucei

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polissacarídeos / Trypanosoma brucei brucei / Proteínas de Protozoários / Glicosiltransferases / Fosfoproteínas Fosfatases Idioma: En Revista: Parasitol Int Assunto da revista: PARASITOLOGIA Ano de publicação: 2014 Tipo de documento: Article

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