Intermediates in monensin biosynthesis: A late step in biosynthesis of the polyether ionophore monensin is crucial for the integrity of cation binding.

Hüttel, Wolfgang; Spencer, Jonathan B; Leadlay, Peter F

Hüttel, Wolfgang; Spencer, Jonathan B; Leadlay, Peter F.

Afiliação

Hüttel W; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK, ; Institute for Pharmaceutical Sciences, Universität Freiburg, Albertstr. 25, 79104 Freiburg, Germany.
Spencer JB; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1QW, UK.
Leadlay PF; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.

Beilstein J Org Chem ; 10: 361-8, 2014.

Article em En | MEDLINE | ID: mdl-24605157

Palavras-chave

Streptomyces; antibiotics; biosynthesis; natural products; polyketides; synthetic biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Beilstein J Org Chem Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Alemanha

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