Development of the First Fluorescence Screening Assay for the SLC39A2 Zinc Transporter.

Franz, Marie-Christine; Simonin, Alexandre; Graeter, Stefanie; Hediger, Matthias A; Kovacs, Gergely

Franz, Marie-Christine; Simonin, Alexandre; Graeter, Stefanie; Hediger, Matthias A; Kovacs, Gergely.

Afiliação

Franz MC; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland Swiss National Center of Competence in Research, NCCR TransCure, University of Bern, Bern, Switzerland.
Simonin A; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland Swiss National Center of Competence in Research, NCCR TransCure, University of Bern, Bern, Switzerland.
Graeter S; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland Swiss National Center of Competence in Research, NCCR TransCure, University of Bern, Bern, Switzerland.
Hediger MA; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland Swiss National Center of Competence in Research, NCCR TransCure, University of Bern, Bern, Switzerland.
Kovacs G; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland Swiss National Center of Competence in Research, NCCR TransCure, University of Bern, Bern, Switzerland gergely.kovacs@ibmm.unibe.ch matthias.hediger@ibmm.unibe.ch.

J Biomol Screen ; 19(6): 909-16, 2014 Jul.

Article em En | MEDLINE | ID: mdl-24619115

Assuntos

Proteínas de Transporte de Cátions/química; Espectrometria de Fluorescência/métodos; Zinco/química; Transporte Biológico; Biotinilação; Cádmio/química; Membrana Celular/metabolismo; Clonagem Molecular; Relação Dose-Resposta a Droga; Fluorescência; Corantes Fluorescentes/química; Células HEK293; Humanos; Íons; Cinética; Masculino; Microscopia de Fluorescência; Próstata/citologia; Reação em Cadeia da Polimerase em Tempo Real

Palavras-chave

FLIPR Tetra; cadmium; cell-based assay; hZIP2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Fluorescência / Zinco / Proteínas de Transporte de Cátions Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans / Male Idioma: En Revista: J Biomol Screen Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Suíça

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