Prevalence of the E318K and V320I MITF germline mutations in Polish cancer patients and multiorgan cancer risk-a population-based study.

Gromowski, Tomasz; Masojc, Bartlomiej; Scott, Rodney J; Cybulski, Cezary; Górski, Bohdan; Kluzniak, Wojciech; Paszkowska-Szczur, Katarzyna; Rozmiarek, Andrzej; Debniak, Boguslaw; Maleszka, Romuald; Kladny, Józef; Lubinski, Jan; Debniak, Tadeusz

Gromowski, Tomasz; Masojc, Bartlomiej; Scott, Rodney J; Cybulski, Cezary; Górski, Bohdan; Kluzniak, Wojciech; Paszkowska-Szczur, Katarzyna; Rozmiarek, Andrzej; Debniak, Boguslaw; Maleszka, Romuald; Kladny, Józef; Lubinski, Jan; Debniak, Tadeusz.

Afiliação

Gromowski T; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland. Electronic address: tomaszbiotech@gmail.com.
Masojc B; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
Scott RJ; Discipline of Medical Genetics, Faculty of Health, University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia.
Cybulski C; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
Górski B; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
Kluzniak W; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
Paszkowska-Szczur K; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
Rozmiarek A; Regional Hospital, Zielona Góra, Poland.
Debniak B; Chair and Clinic of Mother's and Child's Health, Medical University, Poznan, Poland.
Maleszka R; Department of Dermatology and Venereology, Pomeranian Medical University, Szczecin, Poland.
Kladny J; Department of General and Oncological Surgery, Pomeranian Medical University, Szczecin, Poland.
Lubinski J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
Debniak T; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.

Cancer Genet ; 207(4): 128-32, 2014 Apr.

Article em En | MEDLINE | ID: mdl-24767713

Assuntos

Mutação em Linhagem Germinativa; Fator de Transcrição Associado à Microftalmia/genética; Mutação de Sentido Incorreto; Neoplasias/genética; Idoso; Neoplasias da Mama/epidemiologia; Neoplasias da Mama/genética; Distribuição de Qui-Quadrado; Neoplasias do Colo/epidemiologia; Neoplasias do Colo/genética; Feminino; Frequência do Gene; Predisposição Genética para Doença/genética; Genótipo; Humanos; Neoplasias Renais/epidemiologia; Neoplasias Renais/genética; Neoplasias Pulmonares/epidemiologia; Neoplasias Pulmonares/genética; Masculino; Melanoma/epidemiologia; Melanoma/genética; Pessoa de Meia-Idade; Neoplasias/epidemiologia; Polônia/epidemiologia; Vigilância da População; Prevalência; Neoplasias da Próstata/epidemiologia; Neoplasias da Próstata/genética; Fatores de Risco

Palavras-chave

E318K; MITF; c.952G>A; microphthalmia-associated transcription factor, melanoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutação em Linhagem Germinativa / Mutação de Sentido Incorreto / Fator de Transcrição Associado à Microftalmia / Neoplasias Tipo de estudo: Etiology_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Cancer Genet Ano de publicação: 2014 Tipo de documento: Article

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