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Identification of selective small molecule inhibitors of the nucleotide-binding oligomerization domain 1 (NOD1) signaling pathway.
Rickard, David J; Sehon, Clark A; Kasparcova, Viera; Kallal, Lorena A; Haile, Pamela A; Zeng, Xin; Montoute, Monica N; Poore, Derek D; Li, Hu; Wu, Zining; Eidam, Patrick M; Emery, John G; Marquis, Robert W; Gough, Peter J; Bertin, John.
Afiliação
  • Rickard DJ; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Sehon CA; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Kasparcova V; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Kallal LA; Biological Reagents and Assay Development, Platform Technology Sciences, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Haile PA; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Zeng X; Screening and Compound Profiling, Platform Technology Sciences, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Montoute MN; Screening and Compound Profiling, Platform Technology Sciences, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Poore DD; Biological Reagents and Assay Development, Platform Technology Sciences, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Li H; Biological Reagents and Assay Development, Platform Technology Sciences, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Wu Z; Screening and Compound Profiling, Platform Technology Sciences, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Eidam PM; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Emery JG; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Marquis RW; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Gough PJ; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Bertin J; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
PLoS One ; 9(5): e96737, 2014.
Article em En | MEDLINE | ID: mdl-24806487
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xantinas / Transdução de Sinais / Benzotiazóis / Quinazolinonas / Proteína Adaptadora de Sinalização NOD1 Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xantinas / Transdução de Sinais / Benzotiazóis / Quinazolinonas / Proteína Adaptadora de Sinalização NOD1 Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos