Downregulation of SUN2, a novel tumor suppressor, mediates miR-221/222-induced malignancy in central nervous system embryonal tumors.

Hsieh, Tsung-Han; Chien, Chen-Li; Lee, Yu-Hsiu; Lin, Chen-I; Hsieh, Jui-Yu; Chao, Meng-En; Liu, Da-Jung; Chu, Shing-Shiung; Chen, Wan; Lin, Shih-Chieh; Ho, Donald Ming-Tak; Liu, Ren-Shyan; Lin, Chi-Hung; Wong, Tai-Tong; Wang, Hsei-Wei

Hsieh, Tsung-Han; Chien, Chen-Li; Lee, Yu-Hsiu; Lin, Chen-I; Hsieh, Jui-Yu; Chao, Meng-En; Liu, Da-Jung; Chu, Shing-Shiung; Chen, Wan; Lin, Shih-Chieh; Ho, Donald Ming-Tak; Liu, Ren-Shyan; Lin, Chi-Hung; Wong, Tai-Tong; Wang, Hsei-Wei.

Afiliação

Hsieh TH; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei 112, Taiwan, ttwomg99@gmail.com.
Chien CL; Division of Neurosurgery, Department of Surgery, Cheng Hsin General Hospital, Taipei 112, Taiwan, Division of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan, ttwomg99@gmail.com.
Lee YH; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei 112, Taiwan.
Lin CI; Division of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Hsieh JY; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei 112, Taiwan.
Chao ME; Division of Neurosurgery, Department of Surgery, Cheng Hsin General Hospital, Taipei 112, Taiwan, Division of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Liu DJ; Division of Neurosurgery, Department of Surgery, Cheng Hsin General Hospital, Taipei 112, Taiwan, Division of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Chu SS; Division of Neurosurgery, Department of Surgery, Cheng Hsin General Hospital, Taipei 112, Taiwan, Division of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Chen W; Division of Neurosurgery, Department of Surgery, Cheng Hsin General Hospital, Taipei 112, Taiwan, Division of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Lin SC; Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Ho DM; Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan, School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.
Liu RS; School of Medicine, National Yang-Ming University, Taipei 112, Taiwan, National PET/Cyclotron Center, Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan, Molecular and Genetic Imaging Core/Taiwan Mouse Clinic, National Comprehensive Mouse Phenotyping and Drug Testin
Lin CH; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei 112, Taiwan, Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan.
Wong TT; Division of Neurosurgery, Department of Surgery, Cheng Hsin General Hospital, Taipei 112, Taiwan, Division of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan, School of Medicine, National Yang-Ming University, Taipei 112, Taiwan, Cancer Research C
Wang HW; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei 112, Taiwan, Cancer Research Center & Genome Research Center, National Yang-Ming University, Taipei 112, Taiwan, Institute of Clinical Medicine, National Yang-Ming University, Taipei 112, Taiwan and Department of Edu

Carcinogenesis ; 35(10): 2164-74, 2014 Oct.

Article em En | MEDLINE | ID: mdl-24832085

Assuntos

Peptídeos e Proteínas de Sinalização Intracelular/genética; Proteínas de Membrana/genética; MicroRNAs/genética; Neoplasias Embrionárias de Células Germinativas/genética; Animais; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/mortalidade; Neoplasias Cerebelares/genética; Neoplasias Cerebelares/mortalidade; Criança; Pré-Escolar; Regulação para Baixo; Feminino; Regulação Neoplásica da Expressão Gênica; Genes Supressores de Tumor; Humanos; Peptídeos e Proteínas de Sinalização Intracelular/metabolismo; Masculino; Meduloblastoma/genética; Meduloblastoma/mortalidade; Proteínas de Membrana/metabolismo; Camundongos Endogâmicos NOD; Neoplasias Embrionárias de Células Germinativas/mortalidade; Tumores Neuroectodérmicos Primitivos/genética; Tumores Neuroectodérmicos Primitivos/mortalidade; Tumor Rabdoide/genética; Tumor Rabdoide/mortalidade; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Embrionárias de Células Germinativas / MicroRNAs / Peptídeos e Proteínas de Sinalização Intracelular / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Animals / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Carcinogenesis Ano de publicação: 2014 Tipo de documento: Article

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