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Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety.
He, Shuwen; Hong, Qingmei; Lai, Zhong; Wu, Zhicai; Yu, Yang; Kim, David W; Ting, Pauline C; Kuethe, Jeffrey T; Yang, Ginger X; Jian, Tianying; Liu, Jian; Guiadeen, Deodial; Krikorian, Arto D; Sperbeck, Donald M; Sonatore, Lisa M; Wiltsie, Judyann; Chung, Christine C; Gibson, Jack T; Lisnock, JeanMarie; Murphy, Beth A; Gorski, Judith N; Liu, Jinqi; Chen, Dunlu; Chen, Xiaoli; Wolff, Michael; Tong, Sharon X; Madeira, Maria; Karanam, Bindhu V; Shen, Dong-Ming; Balkovec, James M; Pinto, Shirly; Nargund, Ravi P; DeVita, Robert J.
Afiliação
  • He S; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Hong Q; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Lai Z; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Wu Z; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Yu Y; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Kim DW; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Ting PC; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Kuethe JT; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Yang GX; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Jian T; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Liu J; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Guiadeen D; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Krikorian AD; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Sperbeck DM; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Sonatore LM; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Wiltsie J; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Chung CC; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Gibson JT; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Lisnock J; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Murphy BA; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Gorski JN; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Liu J; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Chen D; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Chen X; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Wolff M; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Tong SX; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Madeira M; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Karanam BV; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Shen DM; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Balkovec JM; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Pinto S; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Nargund RP; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • DeVita RJ; Discovery and Preclinical Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
ACS Med Chem Lett ; 4(8): 773-8, 2013 Aug 08.
Article em En | MEDLINE | ID: mdl-24900745
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Estados Unidos