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Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial.
Garon, Edward B; Ciuleanu, Tudor-Eliade; Arrieta, Oscar; Prabhash, Kumar; Syrigos, Konstantinos N; Goksel, Tuncay; Park, Keunchil; Gorbunova, Vera; Kowalyszyn, Ruben Dario; Pikiel, Joanna; Czyzewicz, Grzegorz; Orlov, Sergey V; Lewanski, Conrad R; Thomas, Michael; Bidoli, Paolo; Dakhil, Shaker; Gans, Steven; Kim, Joo-Hang; Grigorescu, Alexandru; Karaseva, Nina; Reck, Martin; Cappuzzo, Federico; Alexandris, Ekaterine; Sashegyi, Andreas; Yurasov, Sergey; Pérol, Maurice.
Afiliação
  • Garon EB; David Geffen School of Medicine at UCLA/Translational Research in Oncology-US Network, Los Angeles, CA, USA. Electronic address: egaron@mednet.ucla.edu.
  • Ciuleanu TE; Institute of Oncology Ion Chiricuta and University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania.
  • Arrieta O; Instituto Nacional de Cancerologia (INCAN), Mexico City, Mexico.
  • Prabhash K; Tata Memorial Centre, Mumbai, India.
  • Syrigos KN; Oncology Unit GPP, Sotiria General Hospital, Athens School of Medicine, Athens, Greece.
  • Goksel T; Ege University School of Medicine, Izmir, Turkey.
  • Park K; Department of Medicine, Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Gorbunova V; Department of Chemotherapy, N N Blokhin Cancer Research Center, Moscow, Russia.
  • Kowalyszyn RD; Centro de Investigaciones Clínicas, Clínica Viedma, Argentina.
  • Pikiel J; Wojewódzkie Centrum Onkologii, Gdansk, Poland.
  • Czyzewicz G; Chemotherapy Department, John Paul II Hospital, Krakow, Poland.
  • Orlov SV; Pavlov State Medical University, St Petersburg, Russia.
  • Lewanski CR; Charing Cross Hospital, London, UK.
  • Thomas M; Internistische Onkologie der Thoraxtumoren, Thoraxklinik im Universitätsklinikum Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), German Center for Lung Research (DZL), Heidelberg, Germany.
  • Bidoli P; Medical Oncology, San Gerardo Hospital, Monza, Italy.
  • Dakhil S; Cancer Center of Kansas, Wichita, KS, USA.
  • Gans S; St Jansdal Hospital, Herderwijk, Netherlands.
  • Kim JH; Yonsei Cancer Center, Yonsei University Health System, Seoul, South Korea.
  • Grigorescu A; Department of Medical Oncology, Institute of Oncology, Bucharest, Romania.
  • Karaseva N; City Clinical Oncology Dispensary, St Petersburg, Russia.
  • Reck M; LungenClinic Grosshansdorf, German Center for Lung Research (DZL), Grosshansdorf, Germany.
  • Cappuzzo F; Istituto Toscano Tumori, Livorno, Italy.
  • Alexandris E; ImClone Systems, Eli Lilly, Bridgewater, NJ, USA.
  • Sashegyi A; Eli Lilly, Indianapolis, IN, USA.
  • Yurasov S; ImClone Systems, Eli Lilly, Bridgewater, NJ, USA.
  • Pérol M; Léon-Bérard Cancer Centre, Lyon, France.
Lancet ; 384(9944): 665-73, 2014 Aug 23.
Article em En | MEDLINE | ID: mdl-24933332
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Ano de publicação: 2014 Tipo de documento: Article