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Randomized, double-blind, placebo-controlled clinical trial of a two-day regimen of dihydroartemisinin-piperaquine for malaria prevention halted for concern over prolonged corrected QT interval.
Manning, Jessica; Vanachayangkul, Pattaraporn; Lon, Chanthap; Spring, Michele; So, Mary; Sea, Darapiseth; Se, Youry; Somethy, Sok; Phann, Sut-Thang; Chann, Soklyda; Sriwichai, Sabaithip; Buathong, Nillawan; Kuntawunginn, Worachet; Mitprasat, Mashamon; Siripokasupkul, Raveewan; Teja-Isavadharm, Paktiya; Soh, Eugene; Timmermans, Ans; Lanteri, Charlotte; Kaewkungwal, Jaranit; Auayporn, Montida; Tang, Douglas; Chour, Char Meng; Prom, Satharath; Haigney, Mark; Cantilena, Louis; Saunders, David.
Afiliação
  • Manning J; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Vanachayangkul P; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Lon C; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Spring M; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • So M; Royal Cambodian Armed Forces, Phnom Penh, Cambodia.
  • Sea D; National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
  • Se Y; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Somethy S; Royal Cambodian Armed Forces, Phnom Penh, Cambodia.
  • Phann ST; National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
  • Chann S; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Sriwichai S; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Buathong N; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Kuntawunginn W; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Mitprasat M; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Siripokasupkul R; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Teja-Isavadharm P; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Soh E; F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Timmermans A; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Lanteri C; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
  • Kaewkungwal J; Center for Excellence in Bioinformatics (BIOPHICS), Mahidol University, Bangkok, Thailand.
  • Auayporn M; Center for Excellence in Bioinformatics (BIOPHICS), Mahidol University, Bangkok, Thailand.
  • Tang D; Fast Track Biologics, Bethesda, Maryland, USA.
  • Chour CM; National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
  • Prom S; Royal Cambodian Armed Forces, Phnom Penh, Cambodia.
  • Haigney M; F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Cantilena L; F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Saunders D; Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science, Bangkok, Thailand David.Saunders@afrims.org.
Antimicrob Agents Chemother ; 58(10): 6056-67, 2014 Oct.
Article em En | MEDLINE | ID: mdl-25092702

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Quinolinas / Artemisininas / Malária / Antimaláricos Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Tailândia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Quinolinas / Artemisininas / Malária / Antimaláricos Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Tailândia