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Lymphodepletion followed by infusion of suicide gene-transduced donor lymphocytes to safely enhance their antitumor effect: a phase I/II study.
Maury, S; Rosenzwajg, M; Redjoul, R; Marcais, A; Xhaard, A; Cherai, M; Cabanne, L; Churlaud, G; Suarez, F; Socié, G; Gregoire, L; Debbache, K; Bernard, C; Beaumont, J-L; Azar, N; Boyer, O; Roudot-Thoraval, F; Cohen, J L; Cordonnier, C; Lemoine, F M; Klatzmann, D.
Afiliação
  • Maury S; 1] AP-HP, Hôpital Henri Mondor, Department of Hematology, DHU Virus-Immunity-Cancer, Créteil, France [2] IMRB, University Paris Est Créteil (UPEC), INSERM U955 team 21, Créteil, France [3] Center for Clinical Investigation in Biotherapy, Créteil, France.
  • Rosenzwajg M; 1] AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy Department, Paris, France [2] AP-HP, Hôpital Pitié-Salpêtrière, Clinical Investigation Center in Biotherapy (CIC-BTi), Paris, France [3] AP-HP, Hôpital Pitié-Salpêtrière, Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France [4] Sorbo
  • Redjoul R; AP-HP, Hôpital Henri Mondor, Department of Hematology, DHU Virus-Immunity-Cancer, Créteil, France.
  • Marcais A; Department of Hematology, Hôpital Necker, Paris, France.
  • Xhaard A; Department of Hematology-Transplantation, Hôpital St Louis, Paris, France.
  • Cherai M; 1] AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy Department, Paris, France [2] AP-HP, Hôpital Pitié-Salpêtrière, Clinical Investigation Center in Biotherapy (CIC-BTi), Paris, France.
  • Cabanne L; AP-HP, Hôpital Henri Mondor, Department of Hematology, DHU Virus-Immunity-Cancer, Créteil, France.
  • Churlaud G; AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy Department, Paris, France.
  • Suarez F; Department of Hematology, Hôpital Necker, Paris, France.
  • Socié G; Department of Hematology-Transplantation, Hôpital St Louis, Paris, France.
  • Gregoire L; Department of Public Health, Créteil, France.
  • Debbache K; AP-HP, Hôpital Henri Mondor, Department of Hematology, DHU Virus-Immunity-Cancer, Créteil, France.
  • Bernard C; 1] AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy Department, Paris, France [2] AP-HP, Hôpital Pitié-Salpêtrière, Clinical Investigation Center in Biotherapy (CIC-BTi), Paris, France [3] AP-HP, Hôpital Pitié-Salpêtrière, Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France.
  • Beaumont JL; Department of Hemapheresis, Etablissement Français du Sang, Créteil, France.
  • Azar N; AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy Department, Paris, France.
  • Boyer O; Sorbonne Universités, UPMC Univ Paris 06, UMR-S INSERM 1135, CIMI-Paris, Paris, France.
  • Roudot-Thoraval F; 1] IMRB, University Paris Est Créteil (UPEC), INSERM U955 team 21, Créteil, France [2] Department of Public Health, Créteil, France.
  • Cohen JL; 1] IMRB, University Paris Est Créteil (UPEC), INSERM U955 team 21, Créteil, France [2] Center for Clinical Investigation in Biotherapy, Créteil, France.
  • Cordonnier C; 1] AP-HP, Hôpital Henri Mondor, Department of Hematology, DHU Virus-Immunity-Cancer, Créteil, France [2] IMRB, University Paris Est Créteil (UPEC), INSERM U955 team 21, Créteil, France.
  • Lemoine FM; 1] AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy Department, Paris, France [2] AP-HP, Hôpital Pitié-Salpêtrière, Clinical Investigation Center in Biotherapy (CIC-BTi), Paris, France [3] Sorbonne Universités, UPMC Univ Paris 06, UMR-S INSERM 1135, CIMI-Paris, Paris, France.
  • Klatzmann D; 1] AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy Department, Paris, France [2] AP-HP, Hôpital Pitié-Salpêtrière, Clinical Investigation Center in Biotherapy (CIC-BTi), Paris, France [3] AP-HP, Hôpital Pitié-Salpêtrière, Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France [4] Sorbo
Leukemia ; 28(12): 2406-10, 2014 Dec.
Article em En | MEDLINE | ID: mdl-25102947
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos / Terapia Genética / Imunoterapia Adotiva / Genes Transgênicos Suicidas / Neoplasias Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos / Terapia Genética / Imunoterapia Adotiva / Genes Transgênicos Suicidas / Neoplasias Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: França