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mTOR inhibition induces compensatory, therapeutically targetable MEK activation in renal cell carcinoma.
Bailey, Sean T; Zhou, Bing; Damrauer, Jeffrey S; Krishnan, Bhavani; Wilson, Harper L; Smith, Aleisha M; Li, Mingqing; Yeh, Jen Jen; Kim, William Y.
Afiliação
  • Bailey ST; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Zhou B; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Damrauer JS; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Krishnan B; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Wilson HL; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Smith AM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Li M; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Yeh JJ; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Department of Pharmacology, Universit
  • Kim WY; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Department of Genetics, University o
PLoS One ; 9(9): e104413, 2014.
Article em En | MEDLINE | ID: mdl-25180793
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Quinases de Proteína Quinase Ativadas por Mitógeno / Inibidores de Proteínas Quinases / Serina-Treonina Quinases TOR / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Quinases de Proteína Quinase Ativadas por Mitógeno / Inibidores de Proteínas Quinases / Serina-Treonina Quinases TOR / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos