Diabetic-induced increased sodium channel activity attenuated by tetracaine in sensory neurons in vitro.

Meerupally, Rathej; Singh, Jitendra Narain; Sharma, Shyam S

Meerupally, Rathej; Singh, Jitendra Narain; Sharma, Shyam S.

Afiliação

Meerupally R; Electrophysiology Laboratory, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar (Mohali) 160 062, Punjab, India.
Singh JN; Electrophysiology Laboratory, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar (Mohali) 160 062, Punjab, India. Electronic address: jnsingh@niper.ac.in.
Sharma SS; Electrophysiology Laboratory, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar (Mohali) 160 062, Punjab, India. Electronic address: sssharma@niper.ac.in.

Biochem Biophys Res Commun ; 453(3): 296-301, 2014 Oct 24.

Article em En | MEDLINE | ID: mdl-25234593

Assuntos

Anestésicos Locais/farmacologia; Diabetes Mellitus Experimental/fisiopatologia; Células Receptoras Sensoriais/efeitos dos fármacos; Canais de Sódio/fisiologia; Tetracaína/farmacologia; Animais; Técnicas In Vitro; Masculino; Ratos; Ratos Sprague-Dawley; Células Receptoras Sensoriais/fisiologia; Canais de Sódio/efeitos dos fármacos

Palavras-chave

Diabetic neuropathy; Dorsal root ganglion; Hyperglycemia; Pain perception; Voltage-gated sodium channel; Whole cell patch clamp

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Receptoras Sensoriais / Tetracaína / Canais de Sódio / Diabetes Mellitus Experimental / Anestésicos Locais Limite: Animals Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Índia

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