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Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing.
Carroll, Jean; Page, Tristan K W; Chiang, Shih-Chieh; Kalmar, Bernadett; Bode, David; Greensmith, Linda; Mckinnon, Peter J; Thorpe, Julian R; Hafezparast, Majid; El-Khamisy, Sherif F.
Afiliação
  • Carroll J; Genome Damage and Stability Center, University of Sussex, Brighton BN1 9RQ, UK.
  • Page TK; School of Life Science, University of Sussex, Brighton BN1 9QG, UK.
  • Chiang SC; Department of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Sheffield S10 2TN, UK.
  • Kalmar B; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Bode D; School of Life Science, University of Sussex, Brighton BN1 9QG, UK.
  • Greensmith L; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Mckinnon PJ; Department of Genetics, St Jude Children's Research Hospital, Memphis, TN 38105-3678, USA and.
  • Thorpe JR; School of Life Science, University of Sussex, Brighton BN1 9QG, UK.
  • Hafezparast M; School of Life Science, University of Sussex, Brighton BN1 9QG, UK s.el-khamisy@sheffield.ac.uk m.hafezparast@sussex.ac.uk.
  • El-Khamisy SF; Genome Damage and Stability Center, University of Sussex, Brighton BN1 9RQ, UK Department of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Sheffield S10 2TN, UK Center of Genomics, Helmy Institute for Medical Sciences, Zewail City of Science and Technology, Giza, Egy
Hum Mol Genet ; 24(3): 828-40, 2015 Feb 01.
Article em En | MEDLINE | ID: mdl-25274775
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superóxido Dismutase / Transcrição Gênica / Proteínas Nucleares / Senilidade Prematura / Proteínas de Ligação a DNA / Neurônios Motores Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superóxido Dismutase / Transcrição Gênica / Proteínas Nucleares / Senilidade Prematura / Proteínas de Ligação a DNA / Neurônios Motores Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido