X-Chromosome complement and estrogen receptor signaling independently contribute to the enhanced TLR7-mediated IFN-&#945; production of plasmacytoid dendritic cells from women.

Laffont, Sophie; Rouquié, Nelly; Azar, Pascal; Seillet, Cyril; Plumas, Joël; Aspord, Caroline; Guéry, Jean-Charles

X-Chromosome complement and estrogen receptor signaling independently contribute to the enhanced TLR7-mediated IFN-α production of plasmacytoid dendritic cells from women.

Laffont, Sophie; Rouquié, Nelly; Azar, Pascal; Seillet, Cyril; Plumas, Joël; Aspord, Caroline; Guéry, Jean-Charles.

Afiliação

Laffont S; INSERM, Unité Mixte de Recherche 1043, Toulouse F-31300, France; Centre National de la Recherche Scientifique, U5282, Toulouse F-31300, France; Centre de Physiopathologie de Toulouse Purpan, Université Toulouse 3, Toulouse F-31300, France;
Rouquié N; INSERM, Unité Mixte de Recherche 1043, Toulouse F-31300, France; Centre National de la Recherche Scientifique, U5282, Toulouse F-31300, France; Centre de Physiopathologie de Toulouse Purpan, Université Toulouse 3, Toulouse F-31300, France;
Azar P; INSERM, Unité Mixte de Recherche 1043, Toulouse F-31300, France; Centre National de la Recherche Scientifique, U5282, Toulouse F-31300, France; Centre de Physiopathologie de Toulouse Purpan, Université Toulouse 3, Toulouse F-31300, France;
Seillet C; INSERM, Unité Mixte de Recherche 1043, Toulouse F-31300, France; Centre National de la Recherche Scientifique, U5282, Toulouse F-31300, France; Centre de Physiopathologie de Toulouse Purpan, Université Toulouse 3, Toulouse F-31300, France;
Plumas J; Recherche et Développement Laboratoire, Etablissement Français du Sang Rhône-Alpes, La Tronche F-38701, France; Université Joseph Fourier, Grenoble F-38041, France; and Immunobiology and Immunotherapy of Cancers, INSERM U823, La Tronche F-38701, France.
Aspord C; Recherche et Développement Laboratoire, Etablissement Français du Sang Rhône-Alpes, La Tronche F-38701, France; Université Joseph Fourier, Grenoble F-38041, France; and Immunobiology and Immunotherapy of Cancers, INSERM U823, La Tronche F-38701, France.
Guéry JC; INSERM, Unité Mixte de Recherche 1043, Toulouse F-31300, France; Centre National de la Recherche Scientifique, U5282, Toulouse F-31300, France; Centre de Physiopathologie de Toulouse Purpan, Université Toulouse 3, Toulouse F-31300, France; Jean-Charles.Guery@inserm.fr.

J Immunol ; 193(11): 5444-52, 2014 Dec 01.

Article em En | MEDLINE | ID: mdl-25339659

Assuntos

Células Dendríticas/fisiologia; Receptor alfa de Estrogênio; Receptor beta de Estrogênio; Genes Ligados ao Cromossomo X; Células-Tronco Hematopoéticas/fisiologia; Receptor 7 Toll-Like/metabolismo; Animais; Diferenciação Celular; Células Cultivadas; Receptor alfa de Estrogênio/genética; Receptor beta de Estrogênio/genética; Feminino; Dosagem de Genes; Genes Ligados ao Cromossomo X/genética; Transplante de Células-Tronco Hematopoéticas; Humanos; Imunidade Inata; Interferon-alfa/metabolismo; Masculino; Camundongos; Camundongos SCID; Transdução de Sinais/genética; Transdução de Sinais/imunologia; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Células-Tronco Hematopoéticas / Receptor alfa de Estrogênio / Receptor beta de Estrogênio / Receptor 7 Toll-Like / Genes Ligados ao Cromossomo X Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Immunol Ano de publicação: 2014 Tipo de documento: Article

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