Circulating donor-specific anti-human leukocyte antigen antibodies and complement C4d deposition are associated with the development of cardiac allograft vasculopathy.

Frank, Renee; Molina, Maria R; Goldberg, Lee R; Wald, Joyce W; Kamoun, Malek; Lal, Priti

Frank, Renee; Molina, Maria R; Goldberg, Lee R; Wald, Joyce W; Kamoun, Malek; Lal, Priti.

Afiliação

Frank R; From the Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, and.
Molina MR; Heart Failure and Cardiac Transplant Program, Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia.
Goldberg LR; Heart Failure and Cardiac Transplant Program, Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia.
Wald JW; Heart Failure and Cardiac Transplant Program, Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia.
Kamoun M; From the Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, and.
Lal P; From the Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, and.

Am J Clin Pathol ; 142(6): 809-15, 2014 Dec.

Article em En | MEDLINE | ID: mdl-25389335

Assuntos

Anticorpos/imunologia; Complemento C4b/metabolismo; Rejeição de Enxerto/imunologia; Antígenos HLA/imunologia; Transplante de Coração; Fragmentos de Peptídeos/metabolismo; Adulto; Idoso; Idoso de 80 Anos ou mais; Aloenxertos/imunologia; Feminino; Rejeição de Enxerto/metabolismo; Humanos; Masculino; Pessoa de Meia-Idade; Estudos Retrospectivos; Doadores de Tecidos; Adulto Jovem

Palavras-chave

Acute antibody-mediated rejection; C4d; Cardiac allograft vasculopathy; Donor-specific antibodies

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Complemento C4b / Transplante de Coração / Rejeição de Enxerto / Antígenos HLA / Anticorpos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Clin Pathol Ano de publicação: 2014 Tipo de documento: Article

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