Both recombinant interleukin-1 (beta) and purified human monocyte interleukin-1 prime human neutrophils for increased oxidative activity and promote neutrophil spreading.
J Leukoc Biol
; 45(5): 389-95, 1989 May.
Article
em En
| MEDLINE
| ID: mdl-2540256
ABSTRACT
Both purified human monocyte interleukin-1 and recombinant interleukin-1 (beta) primed neutrophils for increased superoxide production and chemiluminescence in response to f-met-leu-phe. In addition, purified human monocyte interleukin-1 and recombinant interleukin-1 (beta) altered neutrophil shape. Recombinant interleukin-1 (alpha) used at the same concentration of interleukin-1 (beta) did not prime neutrophils for increased superoxide production after stimulation with f-met-leu-phe. Interleukin-1 expressed by monocytes in response to endotoxin stimulation could act as a modulator of neutrophil function.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Interleucinas
/
Superóxidos
/
Neutrófilos
Limite:
Humans
Idioma:
En
Revista:
J Leukoc Biol
Ano de publicação:
1989
Tipo de documento:
Article