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Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.
Park, Sae Woong; Casalena, Dominick E; Wilson, Daniel J; Dai, Ran; Nag, Partha P; Liu, Feng; Boyce, Jim P; Bittker, Joshua A; Schreiber, Stuart L; Finzel, Barry C; Schnappinger, Dirk; Aldrich, Courtney C.
Afiliação
  • Park SW; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA.
  • Casalena DE; The Broad Institute Probe Development Center, Cambridge, MA 02142, USA.
  • Wilson DJ; Center for Drug Design, University of Minnesota, Minneapolis, MN 55455, USA.
  • Dai R; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN 55455, USA.
  • Nag PP; The Broad Institute Probe Development Center, Cambridge, MA 02142, USA.
  • Liu F; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN 55455, USA.
  • Boyce JP; Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-6604, USA.
  • Bittker JA; The Broad Institute Probe Development Center, Cambridge, MA 02142, USA.
  • Schreiber SL; The Broad Institute Probe Development Center, Cambridge, MA 02142, USA.
  • Finzel BC; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN 55455, USA.
  • Schnappinger D; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address: dis2003@med.cornell.edu.
  • Aldrich CC; Center for Drug Design, University of Minnesota, Minneapolis, MN 55455, USA; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: aldri015@umn.edu.
Chem Biol ; 22(1): 76-86, 2015 Jan 22.
Article em En | MEDLINE | ID: mdl-25556942
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biotina / Mycobacterium tuberculosis Tipo de estudo: Diagnostic_studies Idioma: En Revista: Chem Biol Assunto da revista: BIOLOGIA / BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biotina / Mycobacterium tuberculosis Tipo de estudo: Diagnostic_studies Idioma: En Revista: Chem Biol Assunto da revista: BIOLOGIA / BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos