The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome.

Warkocki, Zbigniew; Schneider, Cornelius; Mozaffari-Jovin, Sina; Schmitzová, Jana; Höbartner, Claudia; Fabrizio, Patrizia; Lührmann, Reinhard

Warkocki, Zbigniew; Schneider, Cornelius; Mozaffari-Jovin, Sina; Schmitzová, Jana; Höbartner, Claudia; Fabrizio, Patrizia; Lührmann, Reinhard.

Afiliação

Warkocki Z; Department of Cellular Biochemistry.
Schneider C; Department of Cellular Biochemistry.
Mozaffari-Jovin S; Department of Cellular Biochemistry.
Schmitzová J; Department of Cellular Biochemistry.
Höbartner C; Research Group of Nucleic Acid Chemistry, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Fabrizio P; Department of Cellular Biochemistry, reinhard.luehrmann@mpibpc.mpg.de patrizia.fabrizio@mpibpc.mpg.de.
Lührmann R; Department of Cellular Biochemistry.

Genes Dev ; 29(1): 94-107, 2015 Jan 01.

Article em En | MEDLINE | ID: mdl-25561498

Assuntos

Adenosina Trifosfatases/metabolismo; RNA Helicases DEAD-box/metabolismo; Proteínas de Saccharomyces cerevisiae/metabolismo; Spliceossomos/metabolismo; Catálise; Coenzimas/metabolismo; Ativação Enzimática; Hidrólise; Ligação Proteica; Proteínas de Saccharomyces cerevisiae/genética

Palavras-chave

ATP hydrolysis; DEAH-box helicase; G-patch protein; Prp2; Spp2; spliceosome activation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Spliceossomos / Adenosina Trifosfatases / Proteínas de Saccharomyces cerevisiae / RNA Helicases DEAD-box Idioma: En Revista: Genes Dev Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2015 Tipo de documento: Article

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