Self-expandable metallic stents vs. plastic stents for endoscopic biliary drainage in hepatocellular carcinoma.
Endoscopy
; 47(6): 508-16, 2015 Jun.
Article
em En
| MEDLINE
| ID: mdl-25590179
ABSTRACT
BACKGROUND AND STUDY AIMS:
The patency of self-expandable metallic stents (SEMS) is known to be better than plastic stents in the palliation of malignant biliary obstruction. However, data are scarce for obstructive jaundice caused by hepatocellular carcinoma (HCC). This study aimed to compare SEMSs and plastic stents for the palliation of obstructive jaundice in unresectable HCC. PATIENTS ANDMETHODS:
A total of 96 patients who underwent endoscopic retrograde biliary drainage with SEMSs or plastic stents were included in this retrospective analysis. The rate of successful biliary drainage, adverse events, stent patency duration, and patient survival were compared between the SEMS (nâ=â36) and plastic stent (nâ=â60) groups.RESULTS:
The rate of successful biliary drainage was similar between the SEMS and plastic stent groups (25/36 [69.4â%] vs. 39/60 [65.0â%]; Pâ=â0.655). Adverse events occurred in 6 patients (16.7â%) in the SEMS group and 13 patients (21.7â%) in the plastic stent group (Pâ=â0.552). The median patency duration was also similar between the two groups (60 vs. 68 days; Pâ=â0.396). The median patient survival was longer in the plastic stent group than in the SEMS group (123 vs. 48 days; Pâ=â0.005).CONCLUSIONS:
SEMSs were not superior to plastic stents for the palliation of malignant biliary obstruction in HCC with regard to successful drainage, stent patency, and adverse events. Patient survival was better in the plastic stent group.âGiven the lower cost, plastic stents could be a favorable option for malignant biliary obstruction caused by HCC.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cuidados Paliativos
/
Stents
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Drenagem
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Colangiopancreatografia Retrógrada Endoscópica
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Carcinoma Hepatocelular
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Icterícia Obstrutiva
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Neoplasias Hepáticas
Tipo de estudo:
Etiology_studies
/
Evaluation_studies
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Endoscopy
Ano de publicação:
2015
Tipo de documento:
Article