Insulin resistance caused by lipotoxicity is related to oxidative stress and endoplasmic reticulum stress in LPL gene knockout heterozygous mice.

Li, Yang-Xue; Han, Ting-Ting; Liu, Yang; Zheng, Shuang; Zhang, Yao; Liu, Wei; Hu, Yao-Min

Li, Yang-Xue; Han, Ting-Ting; Liu, Yang; Zheng, Shuang; Zhang, Yao; Liu, Wei; Hu, Yao-Min.

Afiliação

Li YX; Department of Endocrinology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China. Electronic address: 1756366571@qq.com.
Han TT; Department of Endocrinology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China. Electronic address: htt86226@163.com.
Liu Y; Stem Cell Research Center, Renji Hospital, School of Medicine, Shanghai Jiaotong University, China. Electronic address: liuyangrj@126.com.
Zheng S; Department of Endocrinology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China. Electronic address: alicezhe_2005@qq.com.
Zhang Y; Department of Endocrinology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China. Electronic address: 475511243@qq.com.
Liu W; Department of Endocrinology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China. Electronic address: sue_liuwei@163.com.
Hu YM; Department of Endocrinology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China. Electronic address: amin99@163.com.

Atherosclerosis ; 239(1): 276-82, 2015 Mar.

Article em En | MEDLINE | ID: mdl-25635326

Assuntos

Estresse do Retículo Endoplasmático; Resistência à Insulina; Lipase Lipoproteica/genética; Estresse Oxidativo; Animais; Glicemia/análise; Composição Corporal; Feminino; Glucose/metabolismo; Teste de Tolerância a Glucose; Heterozigoto; Homeostase; Hipertrigliceridemia/patologia; Insulina/metabolismo; Peroxidação de Lipídeos; Fígado/metabolismo; Camundongos; Camundongos Knockout; Músculo Esquelético/metabolismo; Fosforilação; Transdução de Sinais; Fatores de Tempo

Palavras-chave

Endoplasmic reticulum stress; Insulin resistance; Lipoprotein lipase; Oxidative stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Estresse Oxidativo / Estresse do Retículo Endoplasmático / Lipase Lipoproteica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Atherosclerosis Ano de publicação: 2015 Tipo de documento: Article

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