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Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.
Matsuo, Hirotaka; Yamamoto, Ken; Nakaoka, Hirofumi; Nakayama, Akiyoshi; Sakiyama, Masayuki; Chiba, Toshinori; Takahashi, Atsushi; Nakamura, Takahiro; Nakashima, Hiroshi; Takada, Yuzo; Danjoh, Inaho; Shimizu, Seiko; Abe, Junko; Kawamura, Yusuke; Terashige, Sho; Ogata, Hiraku; Tatsukawa, Seishiro; Yin, Guang; Okada, Rieko; Morita, Emi; Naito, Mariko; Tokumasu, Atsumi; Onoue, Hiroyuki; Iwaya, Keiichi; Ito, Toshimitsu; Takada, Tappei; Inoue, Katsuhisa; Kato, Yukio; Nakamura, Yukio; Sakurai, Yutaka; Suzuki, Hiroshi; Kanai, Yoshikatsu; Hosoya, Tatsuo; Hamajima, Nobuyuki; Inoue, Ituro; Kubo, Michiaki; Ichida, Kimiyoshi; Ooyama, Hiroshi; Shimizu, Toru; Shinomiya, Nariyoshi.
Afiliação
  • Matsuo H; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Yamamoto K; Department of Medical Chemistry, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
  • Nakaoka H; Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan.
  • Nakayama A; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan Medical Group, Headquarters, Iwo-to Air Base Group, Japan Air Self-Defense Force, Tokyo, Japan.
  • Sakiyama M; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan Department of Dermatology, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Chiba T; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Takahashi A; Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Yokohama, Kanagawa, Japan.
  • Nakamura T; Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Yokohama, Kanagawa, Japan Laboratory for Mathematics, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Nakashima H; Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Takada Y; The Central Research Institute, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Danjoh I; Cell Engineering Division, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
  • Shimizu S; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Abe J; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Kawamura Y; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Terashige S; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Ogata H; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Tatsukawa S; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Yin G; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan Department of Nutritional Sciences, Faculty of Health and Welfare, Seinan Jo Gakuin University, Fukuoka, Japan.
  • Okada R; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Morita E; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Naito M; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Tokumasu A; Ryougoku East Gate Clinic, Tokyo, Japan.
  • Onoue H; Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Iwaya K; Department of Pathology, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Ito T; Department of Internal Medicine, Self-Defense Forces Central Hospital, Tokyo, Japan.
  • Takada T; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
  • Inoue K; Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Kato Y; Faculty of Pharmacy, Kanazawa University, Kanazawa, Ishikawa, Japan.
  • Nakamura Y; Cell Engineering Division, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan.
  • Sakurai Y; Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Suzuki H; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
  • Kanai Y; Division of Bio-system Pharmacology, Department of Pharmacology, Graduate School of Medicine, Osaka University, Osaka, Japan.
  • Hosoya T; Division of Kidney and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan Department of Pathophysiology and Therapy in Chronic Kidney Disease, Jikei University School of Medicine, Tokyo, Japan.
  • Hamajima N; Department of Healthcare Administration, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Inoue I; Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan.
  • Kubo M; Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Yokohama, Kanagawa, Japan.
  • Ichida K; Division of Kidney and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan Department of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Ooyama H; Ryougoku East Gate Clinic, Tokyo, Japan.
  • Shimizu T; Midorigaoka Hospital, Osaka, Japan.
  • Shinomiya N; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
Ann Rheum Dis ; 75(4): 652-9, 2016 Apr.
Article em En | MEDLINE | ID: mdl-25646370
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hiperuricemia / Gota Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hiperuricemia / Gota Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Japão