Prognostic utility of ischemic response in functional imaging tests (SPECT or stress echocardiography) in low-risk unstable angina patients.
Cardiol J
; 22(2): 160-4, 2015.
Article
em En
| MEDLINE
| ID: mdl-25704055
ABSTRACT
BACKGROUND:
The aim of this study is to determine the ability of ischemic response in imaging stress tests (single-photon emission computed tomography [SPECT] or stress echocardiography [SE]) to predict events in low-risk unstable angina patients.METHODS:
Three hundred and fifty-nine patients with unstable angina (< 24 h), asymptomatic at admission, without ST-segment elevation or depression, normal troponins, and undergoing SPECT (n = 188) or SE (n = 171) during hospitalization (median = 1 day) were included. A positive imaging test (IMAGING+) was defined as the presence of reversible perfusion defects or wall motion abnormalities in at least 2 contiguous segments. Multivariate models were constructed using these results and clinical variables to predict events at 6 months.RESULTS:
Ninety-nine (27%) patients had IMAGING+, 72/188 (38%) in SPECT and 27/17 (16%) in SE (p < 0.0001). Events occurred in 84 (23%) patients 4 had myocardial infarction, 47 new hospitalizations due to angina and 33 coronary artery revascularizations. Independent predictors of coronary artery disease were IMAGING+ (OR 6.4, 95% CI 3.4-11.8, p < 0.0001), history of coronary artery disease (OR 2.5, 95% CI 1.2-5.2, p < 0.02) and TIMI risk (OR 1.5, 95% CI 1.1-2.2, p < 0.03).CONCLUSIONS:
In low-risk unstable angina patients, an ischemic response in functional stress tests (SPECT or SE) was associated with adverse events and severe coronary artery disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença da Artéria Coronariana
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Tomografia Computadorizada de Emissão de Fóton Único
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Ecocardiografia sob Estresse
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Angina Instável
Tipo de estudo:
Etiology_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Cardiol J
Ano de publicação:
2015
Tipo de documento:
Article