X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure-function studies of a neuronal calcium-signalling protein.

Erskine, P T; Fokas, A; Muriithi, C; Rehman, H; Yates, L A; Bowyer, A; Findlow, I S; Hagan, R; Werner, J M; Miles, A J; Wallace, B A; Wells, S A; Wood, S P; Cooper, J B

Erskine, P T; Fokas, A; Muriithi, C; Rehman, H; Yates, L A; Bowyer, A; Findlow, I S; Hagan, R; Werner, J M; Miles, A J; Wallace, B A; Wells, S A; Wood, S P; Cooper, J B.

Afiliação

Erskine PT; Laboratory of Protein Crystallography, Centre for Amyloidosis and Acute Phase Proteins, UCL Division of Medicine (Royal Free Campus), Rowland Hill Street, London NW3 2PF, England.
Fokas A; Laboratory of Protein Crystallography, Centre for Amyloidosis and Acute Phase Proteins, UCL Division of Medicine (Royal Free Campus), Rowland Hill Street, London NW3 2PF, England.
Muriithi C; Laboratory of Protein Crystallography, Centre for Amyloidosis and Acute Phase Proteins, UCL Division of Medicine (Royal Free Campus), Rowland Hill Street, London NW3 2PF, England.
Rehman H; Laboratory of Protein Crystallography, Centre for Amyloidosis and Acute Phase Proteins, UCL Division of Medicine (Royal Free Campus), Rowland Hill Street, London NW3 2PF, England.
Yates LA; Centre of Biological Sciences, University of Southampton, Southampton SO17 1BJ, England.
Bowyer A; Centre of Biological Sciences, University of Southampton, Southampton SO17 1BJ, England.
Findlow IS; Centre of Biological Sciences, University of Southampton, Southampton SO17 1BJ, England.
Hagan R; Centre of Biological Sciences, University of Southampton, Southampton SO17 1BJ, England.
Werner JM; Centre of Biological Sciences, University of Southampton, Southampton SO17 1BJ, England.
Miles AJ; Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, England.
Wallace BA; Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, England.
Wells SA; Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, England.
Wood SP; Laboratory of Protein Crystallography, Centre for Amyloidosis and Acute Phase Proteins, UCL Division of Medicine (Royal Free Campus), Rowland Hill Street, London NW3 2PF, England.
Cooper JB; Laboratory of Protein Crystallography, Centre for Amyloidosis and Acute Phase Proteins, UCL Division of Medicine (Royal Free Campus), Rowland Hill Street, London NW3 2PF, England.

Acta Crystallogr D Biol Crystallogr ; 71(Pt 3): 615-31, 2015 Mar.

Article em En | MEDLINE | ID: mdl-25760610

Assuntos

Proteínas de Ligação ao Cálcio/química; Decapodiformes/química; Simulação de Dinâmica Molecular; Proteínas do Tecido Nervoso/química; Substituição de Aminoácidos; Animais; Proteínas de Ligação ao Cálcio/genética; Proteínas de Ligação ao Cálcio/metabolismo; Cristalografia por Raios X; Decapodiformes/genética; Decapodiformes/metabolismo; Mutação de Sentido Incorreto; Proteínas do Tecido Nervoso/genética; Proteínas do Tecido Nervoso/metabolismo; Estrutura Terciária de Proteína; Relação Estrutura-Atividade

Palavras-chave

EF-hand; calcium signalling; learning; memory; neuronal plasticity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Decapodiformes / Proteínas de Ligação ao Cálcio / Simulação de Dinâmica Molecular / Proteínas do Tecido Nervoso Limite: Animals Idioma: En Revista: Acta Crystallogr D Biol Crystallogr Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido

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