Is dental caries experience increased in HIV-infected children and adolescents? A meta-analysis.
Acta Odontol Scand
; 73(7): 481-7, 2015.
Article
em En
| MEDLINE
| ID: mdl-25765439
ABSTRACT
OBJECTIVE:
To undertake a systematic review to assess if HIV-infected children and adolescents have an increased dental caries experience.METHODS:
A search of MEDLINE, BIREME, EMBASE, GOOGLE SCHOLAR, SIGLE (Grey Literature) and reference lists of included studies was carried out. To be eligible the studies had to present HIV-infected and non-infected children/adolescents between 0-18 years old. To assess the methodological quality, the studies were categorized in scores from 'A' to 'C'. To perform a meta-analysis a random effect model was used with 95% confidence intervals and two distinct sub-group analyses were carried out in terms of caries progression data for cavitated and non-cavitated lesions (sub-group 1) and data only for cavitated lesions (sub-group 2).RESULTS:
Five studies fulfilled the selection criteria. Four studies (two ranked A and two B in the quality assessment) revealed higher caries scores in primary teeth in the HIV-infected patients with mean dmft/dmfs scores of 3.8-4.1/7.8-11.0 compared to the control group 1.5-2.4/3.4-5.1. No differences in caries index were found for permanent dentition. The meta-analysis excluded caries data of permanent teeth and showed a significant association between caries experience in primary dentition and HIV infection considering cavitated and non-cavitated lesions (OR = 2.33, 95% CI = 1.48-3.68) or only cavitated lesions (OR = 2.98, 95% CI = 1.59-5.59).CONCLUSION:
Evidence exists that suggests HIV-infected children/adolescents have an increased caries experience in primary dentition.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Cárie Dentária
Tipo de estudo:
Prognostic_studies
/
Systematic_reviews
Limite:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
Acta Odontol Scand
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Brasil