Tenofovir monotherapy versus tenofovir and entecavir combination therapy in adefovir-resistant chronic hepatitis B patients with multiple drug failure: results of a randomised trial.

Lim, Young-Suk; Yoo, Byung Chul; Byun, Kwan Soo; Kwon, So Young; Kim, Yoon Jun; An, Jihyun; Lee, Han Chu; Lee, Yung Sang

Lim, Young-Suk; Yoo, Byung Chul; Byun, Kwan Soo; Kwon, So Young; Kim, Yoon Jun; An, Jihyun; Lee, Han Chu; Lee, Yung Sang.

Afiliação

Lim YS; Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Yoo BC; Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
Byun KS; Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Kwon SY; Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
Kim YJ; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.
An J; Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Lee HC; Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Lee YS; Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Gut ; 65(6): 1042-51, 2016 06.

Article em En | MEDLINE | ID: mdl-25800784

Assuntos

Antivirais/uso terapêutico; Guanina/análogos & derivados; Hepatite B Crônica/tratamento farmacológico; Tenofovir/uso terapêutico; Adenina/análogos & derivados; Adenina/farmacologia; Adulto; Idoso; Farmacorresistência Viral; Quimioterapia Combinada; Feminino; Guanina/uso terapêutico; Vírus da Hepatite B/enzimologia; Vírus da Hepatite B/genética; Humanos; Masculino; Pessoa de Meia-Idade; Organofosfonatos/farmacologia; República da Coreia; Resultado do Tratamento

Palavras-chave

ANTIVIRAL THERAPY; DRUG RESISTANCE; HEPATITIS B

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Hepatite B Crônica / Tenofovir / Guanina Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Gut Ano de publicação: 2016 Tipo de documento: Article

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