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Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.
Sainz, Bruno; Alcala, Sonia; Garcia, Elena; Sanchez-Ripoll, Yolanda; Azevedo, Maria M; Cioffi, Michele; Tatari, Marianthi; Miranda-Lorenzo, Irene; Hidalgo, Manuel; Gomez-Lopez, Gonzalo; Cañamero, Marta; Erkan, Mert; Kleeff, Jörg; García-Silva, Susana; Sancho, Patricia; Hermann, Patrick C; Heeschen, Christopher.
Afiliação
  • Sainz B; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain.
  • Alcala S; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain.
  • Garcia E; Molecular Diagnostics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Pathology Department, Hospital Universitario Fundacion Alcorcon, Madrid, Spain.
  • Sanchez-Ripoll Y; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Azevedo MM; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Cioffi M; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Tatari M; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Miranda-Lorenzo I; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Hidalgo M; Gastrointestinal Cancer Clinical Research Unit, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Gomez-Lopez G; Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Cañamero M; Histopathology Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Erkan M; Department of Surgery, Klinikum rechts der Isar, Technical University, Munich, Germany Koc University School of Medicine, Istanbul, Turkey.
  • Kleeff J; Department of Surgery, Klinikum rechts der Isar, Technical University, Munich, Germany.
  • García-Silva S; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Sancho P; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Hermann PC; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Deptartment of Internal Medicine I, Ulm University, Ulm, Germany.
  • Heeschen C; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London, UK.
Gut ; 64(12): 1921-35, 2015 Dec.
Article em En | MEDLINE | ID: mdl-25841238
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Células-Tronco Neoplásicas / Carcinoma Ductal Pancreático / Peptídeos Catiônicos Antimicrobianos / Microambiente Tumoral Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Gut Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Espanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Células-Tronco Neoplásicas / Carcinoma Ductal Pancreático / Peptídeos Catiônicos Antimicrobianos / Microambiente Tumoral Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Gut Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Espanha