[Cholangitis with granulocytic epithelial lesion: a new entity with a specific treatment]. / La cholangite à lésion épithéliale granulocytique : une nouvelle entité avec un traitement spécifique.
Ann Pathol
; 35(4): 364-7, 2015 Aug.
Article
em Fr
| MEDLINE
| ID: mdl-26188670
ABSTRACT
Herein, we report a case of cholangitis with granulocytic epithelial lesion associated with pancreatitis in a 22-year-old patient. The association of bile duct lesions and pancreatitis is usually very suggestive of IgG4 related disease. However, in our case, we found no IgG4 tissue infiltration and we found a granulocytic epithelial on the liver biopsy. Recently, cholangitis with granulocytic epithelial lesion was described in the literature. This entity is identified in 2 % of patients with sclerosing cholangitis. Patients are more likely children or young adults and often have an associated inflammatory bowel disease or rarely a pancreatitis. It is defined by the presence of neutrophilic bile duct lesions on a liver biopsy. Although rare, the diagnosis of cholangitis with granulocytic epithelial lesion is important because of its excellent response to immunosuppressive treatment.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Colangite
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Corticosteroides
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Pancreatite Crônica
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Granulócitos
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Imunossupressores
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Prognostic_studies
Limite:
Adult
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Humans
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Male
Idioma:
Fr
Revista:
Ann Pathol
Ano de publicação:
2015
Tipo de documento:
Article