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High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome.
Casina, Veronica C; Hu, Wenbing; Mao, Jian-Hua; Lu, Rui-Nan; Hanby, Hayley A; Pickens, Brandy; Kan, Zhong-Yuan; Lim, Woon K; Mayne, Leland; Ostertag, Eric M; Kacir, Stephen; Siegel, Don L; Englander, S Walter; Zheng, X Long.
Afiliação
  • Casina VC; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;
  • Hu W; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104; engl@mail.med.upenn.edu wenbing@mail.med.upenn.edu zhengl@uab.edu.
  • Mao JH; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;
  • Lu RN; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;
  • Hanby HA; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;
  • Pickens B; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;
  • Kan ZY; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104;
  • Lim WK; Department of Molecular Biology, Pusan National University, Busan, South Korea 609-735;
  • Mayne L; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104;
  • Ostertag EM; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;
  • Kacir S; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;
  • Siegel DL; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;
  • Englander SW; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104; engl@mail.med.upenn.edu wenbing@mail.med.upenn.edu zhengl@uab.edu.
  • Zheng XL; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104; Division of Laboratory Medicine, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249 engl@mail.med.upenn.edu wenbing@mail.med.upenn.edu zhengl@uab.edu.
Proc Natl Acad Sci U S A ; 112(31): 9620-5, 2015 Aug 04.
Article em En | MEDLINE | ID: mdl-26203127
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Púrpura Trombocitopênica Trombótica / Espectrometria de Massas / Mapeamento de Epitopos / Medição da Troca de Deutério Limite: Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Púrpura Trombocitopênica Trombótica / Espectrometria de Massas / Mapeamento de Epitopos / Medição da Troca de Deutério Limite: Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2015 Tipo de documento: Article