The prevalence and significance of a short QT interval in 18,825 low-risk individuals including athletes.
Br J Sports Med
; 50(2): 124-9, 2016 Jan.
Article
em En
| MEDLINE
| ID: mdl-26400956
ABSTRACT
OBJECTIVES:
The short QT syndrome is a cardiac channelopathy characterised by accelerated repolarisation which manifests as a short QT interval on the ECG. The definition of a short QT interval is debated, ranging from <390 to ≤320â ms, and its clinical significance in healthy young individuals is unknown. We assessed the prevalence and medium-term significance of an isolated short QT interval in a diverse young British population.METHODS:
Between 2005 and 2013, 18â 825 apparently healthy people aged 14-35â years underwent cardiovascular evaluation with history, physical examination and ECG. QT intervals were measured by cardiologists using 4 recommended guidelines (Seattle 2013, Heart Rhythm Society 2013, European Society of Cardiology 2010 and American Heart Association 2009).RESULTS:
The prevalence of a short QT interval was 0.1% (26 patients, ≤320â ms), 0.2% (44 patients, ≤330â ms), 7.9% (1478 patients, <380â ms), 15.8% (2973 patients, <390â ms). Male gender and Afro-Caribbean ethnicity had the strongest association with short QT intervals. Athletes had shorter QT intervals than non-athletes but athletic status did not predict short QT intervals. Individuals with short QT intervals ≤320â ms did not report syncope or a sinister family history, and during a follow-up period of 5.3±1.2â years, there were no deaths in this group.CONCLUSIONS:
The prevalence of a short QT interval depends on the recommended cut-off value. Even at values ≤320â ms, there was an excellent medium-term prognosis among 14 people followed. We conclude that a definition of ≤320â ms is realistic to prevent overdiagnosis and excessive investigations.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arritmias Cardíacas
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Esportes
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Canalopatias
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Guideline
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Incidence_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Br J Sports Med
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Reino Unido