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New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.
Okoye-Okafor, Ujunwa C; Bartholdy, Boris; Cartier, Jessy; Gao, Enoch N; Pietrak, Beth; Rendina, Alan R; Rominger, Cynthia; Quinn, Chad; Smallwood, Angela; Wiggall, Kenneth J; Reif, Alexander J; Schmidt, Stanley J; Qi, Hongwei; Zhao, Huizhen; Joberty, Gerard; Faelth-Savitski, Maria; Bantscheff, Marcus; Drewes, Gerard; Duraiswami, Chaya; Brady, Pat; Groy, Arthur; Narayanagari, Swathi-Rao; Antony-Debre, Iléana; Mitchell, Kelly; Wang, Heng Rui; Kao, Yun-Ruei; Christopeit, Maximilian; Carvajal, Luis; Barreyro, Laura; Paietta, Elisabeth; Makishima, Hideki; Will, Britta; Concha, Nestor; Adams, Nicholas D; Schwartz, Benjamin; McCabe, Michael T; Maciejewski, Jaroslav; Verma, Amit; Steidl, Ulrich.
Afiliação
  • Okoye-Okafor UC; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Bartholdy B; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Cartier J; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Gao EN; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Pietrak B; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Rendina AR; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Rominger C; Cancer Epigenetics Discovery Performance Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Quinn C; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Smallwood A; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Wiggall KJ; Cancer Epigenetics Discovery Performance Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Reif AJ; Cancer Epigenetics Discovery Performance Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Schmidt SJ; Cancer Epigenetics Discovery Performance Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Qi H; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Zhao H; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Joberty G; Cellzome, Heidelberg, Germany.
  • Faelth-Savitski M; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Bantscheff M; Cellzome, Heidelberg, Germany.
  • Drewes G; Cellzome, Heidelberg, Germany.
  • Duraiswami C; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Brady P; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Groy A; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Narayanagari SR; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Antony-Debre I; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Mitchell K; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Wang HR; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Kao YR; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Christopeit M; Department of Stem Cell Transplantation, University Medical Center, Hamburg, Germany.
  • Carvajal L; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Barreyro L; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Paietta E; Division of Hemato-Oncology, Department of Medicine (Oncology), Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, New York, USA.
  • Makishima H; Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA.
  • Will B; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Concha N; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Adams ND; Cancer Epigenetics Discovery Performance Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Schwartz B; Department of Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • McCabe MT; Cancer Epigenetics Discovery Performance Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Maciejewski J; Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA.
  • Verma A; Division of Hemato-Oncology, Department of Medicine (Oncology), Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, New York, USA.
  • Steidl U; Department of Developmental &Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
Nat Chem Biol ; 11(11): 878-86, 2015 Nov.
Article em En | MEDLINE | ID: mdl-26436839
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Di-Hidropiridinas / Leucemia Mieloide Aguda / Inibidores Enzimáticos / Isocitrato Desidrogenase Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Di-Hidropiridinas / Leucemia Mieloide Aguda / Inibidores Enzimáticos / Isocitrato Desidrogenase Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos