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Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles.
Verma, Vikas K; Li, Haiyang; Wang, Ruisi; Hirsova, Petra; Mushref, Malek; Liu, Yaming; Cao, Sheng; Contreras, Patricia C; Malhi, Harmeet; Kamath, Patrick S; Gores, Gregory J; Shah, Vijay H.
Afiliação
  • Verma VK; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Li H; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA; Affiliated Hospital of Guiyang Medical College, Guiyang, Guizhou, China.
  • Wang R; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Hirsova P; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Mushref M; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Liu Y; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA; First Hospital of Jilin University, China.
  • Cao S; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Contreras PC; Conatus Pharmaceuticals, San Diego, CA, USA.
  • Malhi H; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Kamath PS; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Gores GJ; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Shah VH; Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. Electronic address: shah.vijay@mayo.edu.
J Hepatol ; 64(3): 651-60, 2016 Mar.
Article em En | MEDLINE | ID: mdl-26632633
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caspases / Hepatócitos / Ligante de CD40 / Etanol / Vesículas Extracelulares / Hepatopatias Alcoólicas / Ativação de Macrófagos Limite: Animals / Female / Humans Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caspases / Hepatócitos / Ligante de CD40 / Etanol / Vesículas Extracelulares / Hepatopatias Alcoólicas / Ativação de Macrófagos Limite: Animals / Female / Humans Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos