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Mice with hepatocyte-specific FXR deficiency are resistant to spontaneous but susceptible to cholic acid-induced hepatocarcinogenesis.
Kong, Bo; Zhu, Yan; Li, Guodong; Williams, Jessica A; Buckley, Kyle; Tawfik, Ossama; Luyendyk, James P; Guo, Grace L.
Afiliação
  • Kong B; Department of Pharmacology and Toxicology, School of Pharmacy, Rutgers University, Piscataway, New Jersey;
  • Zhu Y; Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China;
  • Li G; Department of General Surgery, the Fourth Hospital of Harbin Medical University, Harbin; Division of Biobank Research, Department of General Surgery, the Fourth Hospital of Harbin Medical University, Harbin;
  • Williams JA; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas;
  • Buckley K; Department of Pharmacology and Toxicology, School of Pharmacy, Rutgers University, Piscataway, New Jersey;
  • Tawfik O; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas; and.
  • Luyendyk JP; Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan.
  • Guo GL; Department of Pharmacology and Toxicology, School of Pharmacy, Rutgers University, Piscataway, New Jersey; guo@eohsi.rutgers.edu.
Am J Physiol Gastrointest Liver Physiol ; 310(5): G295-302, 2016 Mar 01.
Article em En | MEDLINE | ID: mdl-26744468
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Receptores Citoplasmáticos e Nucleares / Ciclina D1 / Ácido Cólico / Hepatócitos / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Physiol Gastrointest Liver Physiol Assunto da revista: FISIOLOGIA / GASTROENTEROLOGIA Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Receptores Citoplasmáticos e Nucleares / Ciclina D1 / Ácido Cólico / Hepatócitos / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Physiol Gastrointest Liver Physiol Assunto da revista: FISIOLOGIA / GASTROENTEROLOGIA Ano de publicação: 2016 Tipo de documento: Article