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Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial.
Lonial, Sagar; Weiss, Brendan M; Usmani, Saad Z; Singhal, Seema; Chari, Ajai; Bahlis, Nizar J; Belch, Andrew; Krishnan, Amrita; Vescio, Robert A; Mateos, Maria Victoria; Mazumder, Amitabha; Orlowski, Robert Z; Sutherland, Heather J; Bladé, Joan; Scott, Emma C; Oriol, Albert; Berdeja, Jesus; Gharibo, Mecide; Stevens, Don A; LeBlanc, Richard; Sebag, Michael; Callander, Natalie; Jakubowiak, Andrzej; White, Darrell; de la Rubia, Javier; Richardson, Paul G; Lisby, Steen; Feng, Huaibao; Uhlar, Clarissa M; Khan, Imran; Ahmadi, Tahamtan; Voorhees, Peter M.
Afiliação
  • Lonial S; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, USA. Electronic address: sloni01@emory.edu.
  • Weiss BM; Division of Hematology-Oncology, Department of Medicine, Abramson Cancer Center and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Usmani SZ; Levine Cancer Institute/Carolinas Healthcare System, Charlotte, NC, USA.
  • Singhal S; Robert H Lurie Comprehensive Cancer Center, Division of Hematology/Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Chari A; Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY, USA.
  • Bahlis NJ; Tom Baker Cancer Center, University of Calgary, Calgary, AB, Canada.
  • Belch A; Cross Cancer Institute, Edmonton, AB, Canada.
  • Krishnan A; The Judy and Bernard Briskin Myeloma Center, City of Hope, Duarte, CA, USA.
  • Vescio RA; Cedars-Sinai Outpatient Cancer Center at the Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA.
  • Mateos MV; University Hospital of Salamanca/Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain.
  • Mazumder A; Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY, USA.
  • Orlowski RZ; Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Sutherland HJ; Leukemia/Bone Marrow Transplant Program, University of British Columbia, Vancouver, BC, Canada.
  • Bladé J; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clinic de Barcelona, Barcelona, Spain.
  • Scott EC; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.
  • Oriol A; Institut Català d'Oncologia, Institut Josep Carreras, Hospital Germans Trias i Pujol, Barcelona, Spain.
  • Berdeja J; Sarah Cannon Research Institute, Nashville, TN, USA.
  • Gharibo M; Rutgers Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers, State University of New Jersey, New Brunswick, NJ, USA.
  • Stevens DA; Norton Health Care, Louisville, KY, USA.
  • LeBlanc R; Hôpital Maisonneuve-Rosemont, Montreal, QC, Canada.
  • Sebag M; Royal Victoria Hospital, Montreal, QC, Canada.
  • Callander N; University of Wisconsin Medical School, Madison, WI, USA.
  • Jakubowiak A; University of Chicago Medicine, Chicago, IL, USA.
  • White D; Dalhousie University and Queen Elizabeth II Health Sciences Center, Halifax, NS, Canada.
  • de la Rubia J; Hospital Dr Peset and Universidad Católica San Vicente Mártir, Valencia, Spain.
  • Richardson PG; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Lisby S; Genmab, Copenhagen, Denmark.
  • Feng H; Janssen Research and Development, Raritan, NJ, USA.
  • Uhlar CM; Janssen Research and Development, Spring House, PA, USA.
  • Khan I; Janssen Research and Development, Raritan, NJ, USA.
  • Ahmadi T; Janssen Research and Development, Spring House, PA, USA.
  • Voorhees PM; Division of Hematology and Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Lancet ; 387(10027): 1551-1560, 2016 Apr 09.
Article em En | MEDLINE | ID: mdl-26778538
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais / Mieloma Múltiplo / Recidiva Local de Neoplasia / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Europa Idioma: En Revista: Lancet Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais / Mieloma Múltiplo / Recidiva Local de Neoplasia / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Europa Idioma: En Revista: Lancet Ano de publicação: 2016 Tipo de documento: Article