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Polyanionic Macromolecular Prodrugs of Ribavirin: Antiviral Agents with a Broad Spectrum of Activity.
Hinton, Tracey M; Zuwala, Kaja; Deffrasnes, Celine; Todd, Shawn; Shi, Shuning; Marsh, Glenn A; Dearnley, Megan; Wohl, Benjamin M; Tolstrup, Martin; Zelikin, Alexander N.
Afiliação
  • Hinton TM; CSIRO-Health and Biosecurity Flagship, Australian Animal Health Laboratory, Geelong, VIC, 3220, Australia.
  • Zuwala K; Department of Infectious Diseases, Aarhus University Hospital, 8000, Aarhus C, Denmark.
  • Deffrasnes C; Department of Chemistry and the iNano, Interdisciplinary Nanoscience Centre, Aarhus University, 8000, Aarhus C, Denmark.
  • Todd S; CSIRO-Health and Biosecurity Flagship, Australian Animal Health Laboratory, Geelong, VIC, 3220, Australia.
  • Shi S; CSIRO-Health and Biosecurity Flagship, Australian Animal Health Laboratory, Geelong, VIC, 3220, Australia.
  • Marsh GA; CSIRO-Health and Biosecurity Flagship, Australian Animal Health Laboratory, Geelong, VIC, 3220, Australia.
  • Dearnley M; CSIRO-Health and Biosecurity Flagship, Australian Animal Health Laboratory, Geelong, VIC, 3220, Australia.
  • Wohl BM; CSIRO-Health and Biosecurity Flagship, Australian Animal Health Laboratory, Geelong, VIC, 3220, Australia.
  • Tolstrup M; Department of Chemistry and the iNano, Interdisciplinary Nanoscience Centre, Aarhus University, 8000, Aarhus C, Denmark.
  • Zelikin AN; Department of Infectious Diseases, Aarhus University Hospital, 8000, Aarhus C, Denmark.
Adv Healthc Mater ; 5(5): 534-40, 2016 Mar 09.
Article em En | MEDLINE | ID: mdl-26789641
ABSTRACT
Macromolecular prodrugs are developed as multiarmed agents against diverse viral pathogens. Lead candidates inhibit infectivity and replication of HIV, Ebola, influenza, measles, RSV, etc-thus being broad-spectrum antiviral agents.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Polímeros / Ribavirina / Pró-Fármacos / Substâncias Macromoleculares Limite: Animals / Humans Idioma: En Revista: Adv Healthc Mater Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Polímeros / Ribavirina / Pró-Fármacos / Substâncias Macromoleculares Limite: Animals / Humans Idioma: En Revista: Adv Healthc Mater Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Austrália