Crystal structure of bis-p-anizidinegossypol with an unknown solvate.
Acta Crystallogr E Crystallogr Commun
; 71(Pt 12): 1421-4, 2015 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-26870395
ABSTRACT
The title compound, C44H44N2O8, (systematic name 1,1',6,6'-tetra-hydroxy-5,5'-diisopropyl-8,8'-bis-{[(4-meth-oxy-phen-yl)iminium-yl]meth-yl}-3,3'-dimethyl-2,2'-bi-naphthalene-7,7'-diolate) has been obtained by the addition of p-anizidine to gossypol dissolved in di-chloro-methane. In the solid state, the title compound exists in the enamine or quinoid form. The two naphthyl moieties are inclined to one another by 72.08â
(5)°. The pendant phenyl rings are inclined at 22.26â
(14) and 23.86â
(13)° to the corresponding naphthyl rings. In the crystal, mol-ecules are incorporated into layers through inversion-related pairs of O-Hâ¯O inter-actions [graph sets R 2 (2)(20) and R 2 (2)(10)] and translation-related O-Hâ¯O inter-actions [graph set C(15)]. The packing of these layers in the crystal structure gives rise to channels in the [011] direction, with hydro-phobic inter-actions occurring between adjacent layers. The channels are 5-7â
Å wide, and the void volume of each cell is 655â
Å(3), corresponding to 26.6% of the cell volume. Disordered guest mol-ecules, probably solvent and water mol-ecules, occupy these voids of the crystal; their contribution to the scattering was removed with the SQUEEZE routine [Spek (2015 â¸). Acta Cryst. C71, 9-18] of PLATON [Spek (2009 â¸). Acta Cryst. D65, 148-155].
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MEDLINE
Idioma:
En
Revista:
Acta Crystallogr E Crystallogr Commun
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Uzbequistão