A Specialized Mechanism of Translation Mediated by FXR1a-Associated MicroRNP in Cellular Quiescence.

Bukhari, Syed I A; Truesdell, Samuel S; Lee, Sooncheol; Kollu, Swapna; Classon, Anthony; Boukhali, Myriam; Jain, Esha; Mortensen, Richard D; Yanagiya, Akiko; Sadreyev, Ruslan I; Haas, Wilhelm; Vasudevan, Shobha

Bukhari, Syed I A; Truesdell, Samuel S; Lee, Sooncheol; Kollu, Swapna; Classon, Anthony; Boukhali, Myriam; Jain, Esha; Mortensen, Richard D; Yanagiya, Akiko; Sadreyev, Ruslan I; Haas, Wilhelm; Vasudevan, Shobha.

Afiliação

Bukhari SIA; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Truesdell SS; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Lee S; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Kollu S; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Classon A; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Boukhali M; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Jain E; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Mortensen RD; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Yanagiya A; Department of Biochemistry, Goodman Cancer Research Center, McGill University, Montreal, QC H3A 1A3, Canada.
Sadreyev RI; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Haas W; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Vasudevan S; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: vasudevan.shobha@mgh.harvard.edu.

Mol Cell ; 61(5): 760-773, 2016 Mar 03.

Article em En | MEDLINE | ID: mdl-26942679

Assuntos

Senescência Celular; MicroRNAs/metabolismo; Oócitos/metabolismo; Biossíntese de Proteínas; RNA Mensageiro/metabolismo; Proteínas de Ligação a RNA/metabolismo; Ribonucleoproteínas/metabolismo; Regiões 3' não Traduzidas; Animais; Proteínas Argonautas/genética; Proteínas Argonautas/metabolismo; Sítios de Ligação; Linhagem Celular; Fator de Iniciação Eucariótico 4G/genética; Fator de Iniciação Eucariótico 4G/metabolismo; Exorribonucleases/genética; Exorribonucleases/metabolismo; Perfilação da Expressão Gênica/métodos; Humanos; MicroRNAs/genética; Proteômica/métodos; Capuzes de RNA/genética; Capuzes de RNA/metabolismo; Interferência de RNA; RNA Mensageiro/genética; Proteínas de Ligação a RNA/genética; Proteínas Repressoras/genética; Proteínas Repressoras/metabolismo; Ribonucleoproteínas/genética; Transdução de Sinais; Serina-Treonina Quinases TOR/genética; Serina-Treonina Quinases TOR/metabolismo; Transfecção; Xenopus laevis

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oócitos / Ribonucleoproteínas / Biossíntese de Proteínas / RNA Mensageiro / Proteínas de Ligação a RNA / Senescência Celular / MicroRNAs Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google