Biotinylation: a novel posttranslational modification linking cell autonomous circadian clocks with metabolism.

He, Lan; Hamm, J Austin; Reddy, Alex; Sams, David; Peliciari-Garcia, Rodrigo A; McGinnis, Graham R; Bailey, Shannon M; Chow, Chi-Wing; Rowe, Glenn C; Chatham, John C; Young, Martin E

He, Lan; Hamm, J Austin; Reddy, Alex; Sams, David; Peliciari-Garcia, Rodrigo A; McGinnis, Graham R; Bailey, Shannon M; Chow, Chi-Wing; Rowe, Glenn C; Chatham, John C; Young, Martin E.

Afiliação

He L; Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama;
Hamm JA; Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama;
Reddy A; Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama;
Sams D; Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama;
Peliciari-Garcia RA; Department of Biological Sciences, Federal University of Sao Paulo, Diadema, Sao Paulo, Brazil;
McGinnis GR; Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama;
Bailey SM; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama; and.
Chow CW; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York.
Rowe GC; Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama;
Chatham JC; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama; and.
Young ME; Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama; meyoung@uab.edu.

Am J Physiol Heart Circ Physiol ; 310(11): H1520-32, 2016 06 01.

Article em En | MEDLINE | ID: mdl-27084392

Assuntos

Biotinilação; Carbono-Carbono Liases/metabolismo; Transtornos Cronobiológicos/metabolismo; Relógios Circadianos; Metabolismo Energético; Cardiopatias/metabolismo; Miócitos Cardíacos/metabolismo; Processamento de Proteína Pós-Traducional; Fatores de Transcrição ARNTL/deficiência; Fatores de Transcrição ARNTL/genética; Acetil-CoA Carboxilase/metabolismo; Animais; Biotina/administração & dosagem; Biotina/metabolismo; Proteínas CLOCK/genética; Carbono-Carbono Ligases/metabolismo; Transtornos Cronobiológicos/genética; Transtornos Cronobiológicos/fisiopatologia; Relógios Circadianos/genética; Modelos Animais de Doenças; Predisposição Genética para Doença; Cardiopatias/genética; Cardiopatias/fisiopatologia; Fígado/metabolismo; Masculino; Metilmalonil-CoA Descarboxilase/metabolismo; Camundongos Endogâmicos C57BL; Camundongos Knockout; Mutação; Fenótipo; Piruvato Carboxilase/metabolismo; Simportadores/metabolismo; Fatores de Tempo

Palavras-chave

biotin; chronobiology; heart; liver; metabolism; nutrition

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Carbono-Carbono Liases / Biotinilação / Transtornos Cronobiológicos / Miócitos Cardíacos / Metabolismo Energético / Relógios Circadianos / Cardiopatias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Physiol Heart Circ Physiol Assunto da revista: CARDIOLOGIA / FISIOLOGIA Ano de publicação: 2016 Tipo de documento: Article

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