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SEPT8 modulates ß-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.
Kurkinen, Kaisa M A; Marttinen, Mikael; Turner, Laura; Natunen, Teemu; Mäkinen, Petra; Haapalinna, Fanni; Sarajärvi, Timo; Gabbouj, Sami; Kurki, Mitja; Paananen, Jussi; Koivisto, Anne M; Rauramaa, Tuomas; Leinonen, Ville; Tanila, Heikki; Soininen, Hilkka; Lucas, Fiona R; Haapasalo, Annakaisa; Hiltunen, Mikko.
Afiliação
  • Kurkinen KM; Institute of Biomedicine, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
  • Marttinen M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
  • Turner L; Eisai Ltd., Bernard Katz Building, University College London, London WC1E 6BT, UK.
  • Natunen T; Institute of Biomedicine, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
  • Mäkinen P; Institute of Biomedicine, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
  • Haapalinna F; Institute of Clinical Medicine - Neurology, School of Medicine, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, 70211 Kuopio, Finland.
  • Sarajärvi T; Institute of Biomedicine, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
  • Gabbouj S; Institute of Biomedicine, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
  • Kurki M; Institute of Clinical Medicine - Neurosurgery, School of Medicine, University of Eastern Finland and Neurosurgery of NeuroCenter, Kuopio University Hospital, 70211 Kuopio, Finland.
  • Paananen J; Institute of Clinical Medicine - Neurosurgery, School of Medicine, University of Eastern Finland and Neurosurgery of NeuroCenter, Kuopio University Hospital, 70211 Kuopio, Finland.
  • Koivisto AM; Institute of Clinical Medicine - Neurology, School of Medicine, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, 70211 Kuopio, Finland.
  • Rauramaa T; Institute of Clinical Medicine - Pathology, School of Medicine, University of Eastern Finland and Department of Pathology, Kuopio University Hospital, 70211 Kuopio, Finland.
  • Leinonen V; Institute of Clinical Medicine - Neurosurgery, School of Medicine, University of Eastern Finland and Neurosurgery of NeuroCenter, Kuopio University Hospital, 70211 Kuopio, Finland.
  • Tanila H; Department of Neurobiology, A.I. Virtanen, Institute for Molecular Sciences, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
  • Soininen H; Institute of Clinical Medicine - Neurology, School of Medicine, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, 70211 Kuopio, Finland.
  • Lucas FR; Eisai Ltd., Bernard Katz Building, University College London, London WC1E 6BT, UK.
  • Haapasalo A; Institute of Clinical Medicine - Neurology, School of Medicine, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, 70211 Kuopio, Finland Department of Neurobiology, A.I. Virtanen, Institute for Molecular Sciences, School of Medicine, University of Eastern Finland,
  • Hiltunen M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland Institute of Clinical Medicine - Neurology, School of Medicine, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, 70211 Kuopio, Finland annakaisa.haapasalo@uef.fi m
J Cell Sci ; 129(11): 2224-38, 2016 06 01.
Article em En | MEDLINE | ID: mdl-27084579
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Peptídeos beta-Amiloides / Ácido Aspártico Endopeptidases / Secretases da Proteína Precursora do Amiloide / Septinas Limite: Animals / Humans Idioma: En Revista: J Cell Sci Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Finlândia
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Peptídeos beta-Amiloides / Ácido Aspártico Endopeptidases / Secretases da Proteína Precursora do Amiloide / Septinas Limite: Animals / Humans Idioma: En Revista: J Cell Sci Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Finlândia