Your browser doesn't support javascript.
loading
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs.
Jiang, Jie; Zhu, Qiang; Gendron, Tania F; Saberi, Shahram; McAlonis-Downes, Melissa; Seelman, Amanda; Stauffer, Jennifer E; Jafar-Nejad, Paymaan; Drenner, Kevin; Schulte, Derek; Chun, Seung; Sun, Shuying; Ling, Shuo-Chien; Myers, Brian; Engelhardt, Jeffery; Katz, Melanie; Baughn, Michael; Platoshyn, Oleksandr; Marsala, Martin; Watt, Andy; Heyser, Charles J; Ard, M Colin; De Muynck, Louis; Daughrity, Lillian M; Swing, Deborah A; Tessarollo, Lino; Jung, Chris J; Delpoux, Arnaud; Utzschneider, Daniel T; Hedrick, Stephen M; de Jong, Pieter J; Edbauer, Dieter; Van Damme, Philip; Petrucelli, Leonard; Shaw, Christopher E; Bennett, C Frank; Da Cruz, Sandrine; Ravits, John; Rigo, Frank; Cleveland, Don W; Lagier-Tourenne, Clotilde.
Afiliação
  • Jiang J; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Zhu Q; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gendron TF; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
  • Saberi S; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • McAlonis-Downes M; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Seelman A; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Stauffer JE; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Jafar-Nejad P; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Drenner K; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Schulte D; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Chun S; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Sun S; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Ling SC; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA; Department of Physiology, National University of Singapore, 12 Science Drive 2, Singapore 117549, Singapore.
  • Myers B; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Engelhardt J; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Katz M; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Baughn M; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Platoshyn O; Department of Anesthesiology, University of California, San Diego, La Jolla, CA 92093, USA; Neuroregeneration Laboratory, Sanford Consortium for Regenerative Medicine, 2880 Torrey Pines Scenic Drive, La Jolla, CA 92037, USA.
  • Marsala M; Department of Anesthesiology, University of California, San Diego, La Jolla, CA 92093, USA; Neuroregeneration Laboratory, Sanford Consortium for Regenerative Medicine, 2880 Torrey Pines Scenic Drive, La Jolla, CA 92037, USA; Institute of Neurobiology, Slovak Academy of Sciences, Soltesovej 9, 04001
  • Watt A; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Heyser CJ; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Ard MC; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • De Muynck L; Laboratory of Neurobiology, Vesalius Research Center, Experimental Neurology, Department of Neurosciences, KU Leuven/VIB, 3000 Leuven, Belgium; Department of Neurology, University Hospitals Leuven, 3000 Leuven, Belgium.
  • Daughrity LM; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
  • Swing DA; Mouse Cancer Genetics Program, National Cancer Institute, Frederick, MD 21702, USA.
  • Tessarollo L; Mouse Cancer Genetics Program, National Cancer Institute, Frederick, MD 21702, USA.
  • Jung CJ; Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA.
  • Delpoux A; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Molecular Biology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Utzschneider DT; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Molecular Biology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Hedrick SM; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Molecular Biology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • de Jong PJ; Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA.
  • Edbauer D; German Center for Neurodegenerative Diseases (DZNE), Ludwig-Maximilians University and Munich Cluster of Systems Neurology (SyNergy), Feodor-Lynen Strasse 17, 81377 Munich, Germany.
  • Van Damme P; Laboratory of Neurobiology, Vesalius Research Center, Experimental Neurology, Department of Neurosciences, KU Leuven/VIB, 3000 Leuven, Belgium; Department of Neurology, University Hospitals Leuven, 3000 Leuven, Belgium.
  • Petrucelli L; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
  • Shaw CE; Institute of Psychiatry, King's College London, London WC2R 2LS, UK.
  • Bennett CF; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Da Cruz S; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Ravits J; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Rigo F; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Cleveland DW; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Lagier-Tourenne C; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: clagier-tourenne@mgh.harvard.edu.
Neuron ; 90(3): 535-50, 2016 05 04.
Article em En | MEDLINE | ID: mdl-27112497
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Oligonucleotídeos Antissenso / Fatores de Troca do Nucleotídeo Guanina / Demência Frontotemporal / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Oligonucleotídeos Antissenso / Fatores de Troca do Nucleotídeo Guanina / Demência Frontotemporal / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos