Ethnic differences: Is there an Asian phenotype for polycystic ovarian syndrome?
Best Pract Res Clin Obstet Gynaecol
; 37: 46-55, 2016 Nov.
Article
em En
| MEDLINE
| ID: mdl-27289337
ABSTRACT
Ethnicity has not been accounted for in the diagnostic criteria for polycystic ovarian syndrome (PCOS). It is increasingly recognised that ethnic differences are likely contributors to the differing manifestations of PCOS. Generally, rates of PCOS may be lower in East Asians. It is clear that East Asians are less hirsute than Caucasians. Hirsutism cut-off thresholds need to be lower in East Asian populations than in Caucasian populations. Despite population-adjusted scoring, Caucasians have higher hirsutism rates among patients diagnosed with PCOS. Rates of hyperandrogenaemia do not appear to differ among PCOS subjects, although serum androstenedione appeared to be higher in Caucasians in one study. Interestingly, higher prevalence of the polycystic ovarian morphology has been reported in East Asian PCOS populations than in Caucasian PCOS subjects. Hence, there is a need for comparative studies across different ethnicities to establish whether epidemiological differences observed reflect a true ethnic difference in the phenotype of PCOS and whether there is an Asian phenotype for PCOS.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenótipo
/
Síndrome do Ovário Policístico
/
Hiperandrogenismo
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Povo Asiático
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Hirsutismo
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
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Prevalence_studies
/
Risk_factors_studies
Limite:
Female
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Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Best Pract Res Clin Obstet Gynaecol
Assunto da revista:
GINECOLOGIA
/
OBSTETRICIA
Ano de publicação:
2016
Tipo de documento:
Article