Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates.
Int J Parasitol
; 46(11): 679-83, 2016 10.
Article
em En
| MEDLINE
| ID: mdl-27456552
ABSTRACT
Plasmodium vivax is the most geographically widespread malaria parasite. Unique features of transmission biology complicate P. vivax control. Interventions targeting transmission are required for malaria eradication. In the absence of an in vitro culture, transmission studies rely on live isolates from non-human primates or endemic regions. Here, we demonstrate P. vivax gametocytes from both India and Brazil are stable during cryopreservation. Importantly, cryopreserved gametocytes from Brazil were capable of infecting three anopheline mosquito species in feedings done in the United States. These findings create new opportunities for transmission studies in diverse locales.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmodium vivax
/
Criopreservação
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Malária Vivax
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Insetos Vetores
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Anopheles
Limite:
Animals
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Humans
País/Região como assunto:
America do sul
/
Asia
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Brasil
Idioma:
En
Revista:
Int J Parasitol
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Estados Unidos