Mitochondrial nitric oxide production supported by reverse electron transfer.

Bombicino, Silvina S; Iglesias, Darío E; Zaobornyj, Tamara; Boveris, Alberto; Valdez, Laura B

Bombicino, Silvina S; Iglesias, Darío E; Zaobornyj, Tamara; Boveris, Alberto; Valdez, Laura B.

Afiliação

Bombicino SS; Institute of Biochemistry and Molecular Medicine, Physical Chemistry Division, School of Pharmacy and Biochemistry, University of Buenos Aires (IBIMOL, UBA-CONICET), Junín 956, C1113AAD, Buenos Aires, Argentina. Electronic address: sbombicino@ffyb.uba.ar.
Iglesias DE; Institute of Biochemistry and Molecular Medicine, Physical Chemistry Division, School of Pharmacy and Biochemistry, University of Buenos Aires (IBIMOL, UBA-CONICET), Junín 956, C1113AAD, Buenos Aires, Argentina.
Zaobornyj T; Institute of Biochemistry and Molecular Medicine, Physical Chemistry Division, School of Pharmacy and Biochemistry, University of Buenos Aires (IBIMOL, UBA-CONICET), Junín 956, C1113AAD, Buenos Aires, Argentina.
Boveris A; Institute of Biochemistry and Molecular Medicine, Physical Chemistry Division, School of Pharmacy and Biochemistry, University of Buenos Aires (IBIMOL, UBA-CONICET), Junín 956, C1113AAD, Buenos Aires, Argentina.
Valdez LB; Institute of Biochemistry and Molecular Medicine, Physical Chemistry Division, School of Pharmacy and Biochemistry, University of Buenos Aires (IBIMOL, UBA-CONICET), Junín 956, C1113AAD, Buenos Aires, Argentina.

Arch Biochem Biophys ; 607: 8-19, 2016 10 01.

Article em En | MEDLINE | ID: mdl-27523732

Assuntos

Mitocôndrias/metabolismo; Óxido Nítrico/metabolismo; Trifosfato de Adenosina/química; Animais; Catálise; Bovinos; Relação Dose-Resposta a Droga; Elétrons; Mitocôndrias Cardíacas/metabolismo; Miocárdio/metabolismo; Álcool Oxidorredutases Dependentes de NAD(+) e NADP(+)/metabolismo; NADP/química; Consumo de Oxigênio; Ratos; Proteínas Recombinantes/química; Rotenona/química; Partículas Submitocôndricas/química; Ácido Succínico/química

Palavras-chave

Complex I; FMN; HbO(2); Inside-out particles; Mitochondrial nitric oxide synthase; Nitric oxide; O(2)(â¢-); RET; Reverse electron transfer; flavin mononucleotide; mitochondrial nitric oxide synthase; mtNOS; oxyhemoglobin; proton electrochemical potential; proton motive force; reverse electron transfer; superoxide anion; Δp; ΔµH(+)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mitocôndrias / Óxido Nítrico Limite: Animals Idioma: En Revista: Arch Biochem Biophys Ano de publicação: 2016 Tipo de documento: Article

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