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Differential Releases of Dopamine and Neuropeptide Y from Histamine-Stimulated PC12 Cells Detected by an Aptamer-Modified Nanowire Transistor.
Banerjee, Subhasree; Hsieh, Ying-Jhu; Liu, Chia-Rung; Yeh, Nai-Hsing; Hung, Hui-Hsing; Lai, Yew-Seng; Chou, Ai-Chuan; Chen, Yit-Tsong; Pan, Chien-Yuan.
Afiliação
  • Banerjee S; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 106, Taiwan.
  • Hsieh YJ; Institute of Atomic and Molecular Sciences, Academia Sinica, P.O. Box 23-166, Taipei, 106, Taiwan.
  • Liu CR; Department of Life Science, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 106, Taiwan.
  • Yeh NH; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 106, Taiwan.
  • Hung HH; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 106, Taiwan.
  • Lai YS; Department of Life Science, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 106, Taiwan.
  • Chou AC; Department of Life Science, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 106, Taiwan.
  • Chen YT; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 106, Taiwan.
  • Pan CY; Department of Life Science, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 106, Taiwan.
Small ; 12(40): 5524-5529, 2016 Oct.
Article em En | MEDLINE | ID: mdl-27551968
ABSTRACT
Silicon nanowire field-effect transistors modified with specific aptamers can directly detect the minute dopamine and neuropeptide Y released from cells. The binding of these molecules to the aptamers results in a conductance change of the transistor biosensor and illustrates the differential releasing mechanisms of these molecules stored in various vesicle pools.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transistores Eletrônicos / Neuropeptídeo Y / Dopamina / Histamina / Aptâmeros de Peptídeos / Nanofios Limite: Animals Idioma: En Revista: Small Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Taiwan

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transistores Eletrônicos / Neuropeptídeo Y / Dopamina / Histamina / Aptâmeros de Peptídeos / Nanofios Limite: Animals Idioma: En Revista: Small Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Taiwan