Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy.

Lu, Kuangda; He, Chunbai; Guo, Nining; Chan, Christina; Ni, Kaiyuan; Weichselbaum, Ralph R; Lin, Wenbin

Lu, Kuangda; He, Chunbai; Guo, Nining; Chan, Christina; Ni, Kaiyuan; Weichselbaum, Ralph R; Lin, Wenbin.

Afiliação

Lu K; Department of Chemistry, The University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.
He C; Department of Chemistry, The University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.
Guo N; Department of Chemistry, The University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.
Chan C; Department of Radiation and Cellular Oncology and The Ludwig Center for Metastasis Research, The University of Chicago , Chicago, Illinois 60637, United States.
Ni K; Department of Chemistry, The University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.
Weichselbaum RR; Department of Chemistry, The University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.
Lin W; Department of Radiation and Cellular Oncology and The Ludwig Center for Metastasis Research, The University of Chicago , Chicago, Illinois 60637, United States.

J Am Chem Soc ; 138(38): 12502-10, 2016 09 28.

Article em En | MEDLINE | ID: mdl-27575718

Assuntos

Neoplasias Colorretais/tratamento farmacológico; Imunoterapia/métodos; Nanopartículas Metálicas/química; Estruturas Metalorgânicas/química; Fotoquimioterapia; Porfirinas/química; Animais; Neoplasias Colorretais/metabolismo; Sistemas de Liberação de Medicamentos; Indolamina-Pirrol 2,3,-Dioxigenase/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Células Neoplásicas Circulantes; Oxigênio Singlete/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fotoquimioterapia / Porfirinas / Neoplasias Colorretais / Nanopartículas Metálicas / Estruturas Metalorgânicas / Imunoterapia Limite: Animals Idioma: En Revista: J Am Chem Soc Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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