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Development, synthesis and structure-activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei.
Seufert, Florian; Kuhn, Maximilian; Hein, Michael; Weiwad, Matthias; Vivoli, Mirella; Norville, Isobel H; Sarkar-Tyson, Mitali; Marshall, Laura E; Schweimer, Kristian; Bruhn, Heike; Rösch, Paul; Harmer, Nicholas J; Sotriffer, Christoph A; Holzgrabe, Ulrike.
Afiliação
  • Seufert F; Institute for Pharmacy and Food Chemistry, University of Würzburg, 97074 Würzburg, Germany.
  • Kuhn M; Institute for Pharmacy and Food Chemistry, University of Würzburg, 97074 Würzburg, Germany.
  • Hein M; Institute for Pharmacy and Food Chemistry, University of Würzburg, 97074 Würzburg, Germany.
  • Weiwad M; Research Center for Enzymology of Proteinfolding, Max-Planck-Institute Halle, 06120 Halle, Germany.
  • Vivoli M; School of Biosciences, University of Exeter, Exeter, United Kingdom.
  • Norville IH; Defence Science and Technology Laboratory, Biomedical Sciences, Porton Down, Salisbury, Wiltshire SP4 0JQ, United Kingdom.
  • Sarkar-Tyson M; Defence Science and Technology Laboratory, Biomedical Sciences, Porton Down, Salisbury, Wiltshire SP4 0JQ, United Kingdom; Marshall Center for Infectious Disease Research and Training, School of Pathology and Laboratory Medicine, University of Western Australia, Perth, Australia.
  • Marshall LE; Defence Science and Technology Laboratory, Biomedical Sciences, Porton Down, Salisbury, Wiltshire SP4 0JQ, United Kingdom.
  • Schweimer K; Department of Biopolymers, University of Bayreuth, Universitätsstrasse 30, 95447 Bayreuth, Germany.
  • Bruhn H; Institute for Molecular Infection Biology, University of Würzburg, 97080 Würzburg, Germany.
  • Rösch P; Department of Biopolymers, University of Bayreuth, Universitätsstrasse 30, 95447 Bayreuth, Germany.
  • Harmer NJ; School of Biosciences, University of Exeter, Exeter, United Kingdom.
  • Sotriffer CA; Institute for Pharmacy and Food Chemistry, University of Würzburg, 97074 Würzburg, Germany.
  • Holzgrabe U; Institute for Pharmacy and Food Chemistry, University of Würzburg, 97074 Würzburg, Germany. Electronic address: ulrike.holzgrabe@uni-wuerzburg.de.
Bioorg Med Chem ; 24(21): 5134-5147, 2016 11 01.
Article em En | MEDLINE | ID: mdl-27591009
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Burkholderia pseudomallei / Legionella pneumophila / Peptidilprolil Isomerase / Inibidores Enzimáticos Tipo de estudo: Prognostic_studies Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Burkholderia pseudomallei / Legionella pneumophila / Peptidilprolil Isomerase / Inibidores Enzimáticos Tipo de estudo: Prognostic_studies Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha