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A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.
Notta, Faiyaz; Chan-Seng-Yue, Michelle; Lemire, Mathieu; Li, Yilong; Wilson, Gavin W; Connor, Ashton A; Denroche, Robert E; Liang, Sheng-Ben; Brown, Andrew M K; Kim, Jaeseung C; Wang, Tao; Simpson, Jared T; Beck, Timothy; Borgida, Ayelet; Buchner, Nicholas; Chadwick, Dianne; Hafezi-Bakhtiari, Sara; Dick, John E; Heisler, Lawrence; Hollingsworth, Michael A; Ibrahimov, Emin; Jang, Gun Ho; Johns, Jeremy; Jorgensen, Lars G T; Law, Calvin; Ludkovski, Olga; Lungu, Ilinca; Ng, Karen; Pasternack, Danielle; Petersen, Gloria M; Shlush, Liran I; Timms, Lee; Tsao, Ming-Sound; Wilson, Julie M; Yung, Christina K; Zogopoulos, George; Bartlett, John M S; Alexandrov, Ludmil B; Real, Francisco X; Cleary, Sean P; Roehrl, Michael H; McPherson, John D; Stein, Lincoln D; Hudson, Thomas J; Campbell, Peter J; Gallinger, Steven.
Afiliação
  • Notta F; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Chan-Seng-Yue M; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Lemire M; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Li Y; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Wilson GW; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Connor AA; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Denroche RE; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Liang SB; UHN Program in BioSpecimen Sciences, Department of Pathology, University Health Network, Toronto, Ontario M5G 2C4, Canada.
  • Brown AM; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Kim JC; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Wang T; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
  • Simpson JT; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
  • Beck T; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
  • Borgida A; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Buchner N; Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada.
  • Chadwick D; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Hafezi-Bakhtiari S; Eppley Institute for Research in Cancer, Nebraska Medical Center, Omaha, Nebraska 68198, USA.
  • Dick JE; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Heisler L; UHN Program in BioSpecimen Sciences, Department of Pathology, University Health Network, Toronto, Ontario M5G 2C4, Canada.
  • Hollingsworth MA; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Ibrahimov E; UHN Program in BioSpecimen Sciences, Department of Pathology, University Health Network, Toronto, Ontario M5G 2C4, Canada.
  • Jang GH; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Johns J; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
  • Jorgensen LG; Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, Ontario M5G 2M9, Canada.
  • Law C; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Ludkovski O; Eppley Institute for Research in Cancer, Nebraska Medical Center, Omaha, Nebraska 68198, USA.
  • Lungu I; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Ng K; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Pasternack D; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Petersen GM; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Shlush LI; Division of Surgical Oncology, Sunnybrook Health Sciences Centre, Odette Cancer Centre, Toronto, Ontario M4N 3M5, Canada.
  • Timms L; Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, Ontario M5G 2M9, Canada.
  • Tsao MS; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Wilson JM; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Yung CK; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Zogopoulos G; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.
  • Bartlett JM; Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, Ontario M5G 2M9, Canada.
  • Alexandrov LB; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Real FX; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
  • Cleary SP; Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, Ontario M5G 2M9, Canada.
  • Roehrl MH; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • McPherson JD; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Stein LD; Research Institute of the McGill University Health Centre, Montreal, Québec, Canada, H3H 2L9.
  • Hudson TJ; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
  • Campbell PJ; Theoretical Biology and Biophysics (T-6) and Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, New Mexico, USA, 87545.
  • Gallinger S; Epithelial Carcinogenesis Group, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
Nature ; 538(7625): 378-382, 2016 Oct 20.
Article em En | MEDLINE | ID: mdl-27732578
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Rearranjo Gênico / Genoma Humano / Mutagênese / Carcinogênese / Modelos Biológicos Tipo de estudo: Prognostic_studies / Screening_studies Limite: Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Rearranjo Gênico / Genoma Humano / Mutagênese / Carcinogênese / Modelos Biológicos Tipo de estudo: Prognostic_studies / Screening_studies Limite: Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá