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Genetic and pharmacological correction of aberrant dopamine synthesis using patient iPSCs with BH4 metabolism disorders.
Ishikawa, Taizo; Imamura, Keiko; Kondo, Takayuki; Koshiba, Yasushi; Hara, Satoshi; Ichinose, Hiroshi; Furujo, Mahoko; Kinoshita, Masako; Oeda, Tomoko; Takahashi, Jun; Takahashi, Ryosuke; Inoue, Haruhisa.
Afiliação
  • Ishikawa T; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Japan.
  • Imamura K; Sumitomo Dainippon Pharma, 3-1-98 Kasugadenaka, Konohana-ku, Osaka, Japan.
  • Kondo T; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Japan.
  • Koshiba Y; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Japan.
  • Hara S; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Japan.
  • Ichinose H; Department of Neurology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Japan.
  • Furujo M; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
  • Kinoshita M; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
  • Oeda T; Department of Pediatrics, Okayama Medical Center, National Hospital Organization, Okayama, Japan.
  • Takahashi J; Department of Neurology, Utano National Hospital, National Hospital Organization, Kyoto, Japan.
  • Takahashi R; Department of Neurology, Utano National Hospital, National Hospital Organization, Kyoto, Japan.
  • Inoue H; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Japan.
Hum Mol Genet ; 25(23): 5188-5197, 2016 12 01.
Article em En | MEDLINE | ID: mdl-27798097
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Biopterinas / Dopamina / Células-Tronco Pluripotentes Induzidas / Doenças Metabólicas Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Japão
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Biopterinas / Dopamina / Células-Tronco Pluripotentes Induzidas / Doenças Metabólicas Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Japão