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In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation.
Sager, Jennifer E; Tripathy, Sasmita; Price, Lauren S L; Nath, Abhinav; Chang, Justine; Stephenson-Famy, Alyssa; Isoherranen, Nina.
Afiliação
  • Sager JE; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA.
  • Tripathy S; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA.
  • Price LS; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA.
  • Nath A; Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, WA, USA.
  • Chang J; Department of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, WA, USA.
  • Stephenson-Famy A; Department of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, WA, USA.
  • Isoherranen N; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA. Electronic address: ni2@uw.edu.
Biochem Pharmacol ; 123: 85-96, 2017 Jan 01.
Article em En | MEDLINE | ID: mdl-27836670
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bupropiona / Citocromo P-450 CYP2D6 Limite: Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bupropiona / Citocromo P-450 CYP2D6 Limite: Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos